HLA-B73

major histocompatibility complex (human), class I, B73
Alleles B*7301
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*7301
Locus chr.6 6p21.31

HLA-B73 (B73) is an HLA-B serotype. The serotype identifies the HLA-B*7301 gene product.[1] Part of B*7301 is similar to the HLA-B22 family, however part resembles the domains seen in other apes.[2] B73 is more common in Western Indian Ocean, Mediterranean and Africa. (For terminology help see: HLA-serotype tutorial)

Serotype

B73 serotype recognition of B*7301 allele-group gene products[3]
B*73B73 OtherSample
allele%%size (N)
73012269106

B*7301 frequencies

HLA B*7301 frequencies
freq
ref.Population(%)
[4]Parsi (Karachi, Pakistan)4.9
[4]United Arab Emirates2.0
[4]Italy2.0
[4]Seri (Sonora, Mexico)1.5
[4]Purépecha (Michoacán, Mexico)1.5
[4]Jews (Israel) (*2 studies)1.2
[4]Beti (Cameroon)1.1
[4]Casablanca (Morocco)0.9
[4]Tbilisi (Georgia)0.9
[4]Mossi (Burkina Faso)0.9
[4]Bulgaria0.9
[4]Sudanese0.8
[4]Tuva (Russia) (2)0.8
[4]Oman0.8
[4]Bamileke (Cameroon)0.6
[4]Pathan (Pakistan)0.5
[4]Khalkha (Mongolia)0.5
[4]Druse Arabs (Israel)0.5
[4]Baloch (Iran)0.5
[4]Manchester (England)0.5
[4]Algeria (1)0.5
[4]Turkey0.4
[4]Amman (Jordan)0.3
[4]Shona (Harare, Zimbabwe)0.2
[4]Republic of Macedonia0.2
[4]Nandi (Kenya)0.2
[4]Luo (Kenya)0.2
[4]Campania (Italy)0.2
[4]Greece0.2

References

  1. Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
  2. Hoffmann HJ, Kristensen TJ, Jensen TG, Graugaard B, Lamm LU (1995). "Antigenic characteristics and cDNA sequences of HLA-B73". Eur. J. Immunogenet. 22 (3): 231–40. doi:10.1111/j.1744-313X.1995.tb00237.x. PMID 8547229.
  3. derived from IMGT/HLA
  4. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. External link in |title= (help)
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