HLA-B18

major histocompatibility complex (human), class I, B18
Alleles B*1801
Alleles B*1802
Alleles B*1803
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*1801
EBI-HLA B*1802
EBI-HLA B*1803
Locus chr.6 6p21.31

HLA-B18 (B18) is an HLA-B serotype. The serotype identifies the more common HLA-B*18 gene products.[1] (For terminology help see: HLA-serotype tutorial) B*1801, the most common allele is at highest frequencies in Northern Italy and the Balkans, a peak frequency distribution it shares with B*3501.

Serotype

B18 serotype recognition of Some HLA B*18 allele-group gene products[2]
B*18B18 Sample
allele%%size (N)
1801961641
18029031
18038329

Allele frequencies

HLA B*1801 frequencies
freq
ref.Population(%)
[3]Italy North pop 116.7
[3]Croatia11.3
[3]Georgia Svaneti Svans11.3
[3]Romanian11.3
[3]Portugal South11.2
[3]Singapore Riau Malay9.9
[3]Bulgaria9.1
[3]Israel Arab Druse8.5
[3]Azores Central Islands8.0
[3]Portugal Centre8.0
[3]Finland7.8
[3]Azores Santa Maria and Sao Miguel7.7
[3]Czech Republic7.5
[3]India Jalpaiguri Toto7.5
[3]Iran Baloch7.1
[3]Philippines Ivatan7.0
[3]Thailand6.7
[3]Tunisia6.7
[3]Portugal North6.5
[3]Zimbabwe Harare Shona6.4
[3]Madeira6.2
[3]Mexico Mestizos6.1
[3]Kenya5.9
[3]Belgium5.1
[3]Morocco Nador Metalsa Class I5.1
[3]Singapore Javanese Indonesians5.1
[3]Israel Ashkenazi and Non Ashkenazi Jews5.0
[3]Uganda Kampala5.0
[3]Kenya Nandi4.8
[3]Oman4.7
[3]Georgia Tibilisi Georgians4.6
[3]Bulgaria Gipsy4.5
[3]France South East4.3
[3]Kenya Luo4.3
[3]Ireland South4.2
[3]Russia Arkhangelsk Pomors4.0
[3]Azores Terceira Island3.9
[3]Guinea Bissau3.8
[3]India New Delhi3.8
[3]Spain Eastern Andalusia Gipsy3.5
[3]Australia New South Wales3.4
[3]Georgia Tibilisi Kurds3.4
[3]Zambia Lusaka3.4
[3]Cameroon Yaounde2.7
[3]Senegal Niokholo Mandenka2.7
[3]Cameroon Beti2.3
[3]Ivory Coast Akan Adiopodoume2.3
[3]Sudanese2.3
[3]Saudi Arabia Guraiat and Hail2.2
[3]South African Natal Zulu2.0
[3]Thailand2.0
[3]India Mumbai Marathas1.9
[3]New Caledonia1.9
[3]Papua New Guinea Wanigela1.5
[3]Cameroon Bamileke1.3

References

  1. ↑ Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
  2. ↑ derived from IMGT/HLA
  3. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. External link in |title= (help)
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