Guanosine-diphosphatase

guanosine-diphosphatase
Identifiers
EC number 3.6.1.42
CAS number 98037-56-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a guanosine-diphosphatase (EC 3.6.1.42) is an enzyme that catalyzes the chemical reaction

GDP + H2O GMP + phosphate

Thus, the two substrates of this enzyme are GDP and H2O, whereas its two products are GMP and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is GDP phosphohydrolase. This enzyme is also called GDPase.

References

    • Raychaudhuri P, Ghosh S, Maitra U (1985). "Purification and characterization of a guanosine diphosphatase activity from calf liver microsomal salt wash proteins". J. Biol. Chem. 260 (14): 8306&ndash, 11. PMID 2989286.
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