Glucose-1-phosphatase
| glucose-1-phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.3.10 | ||||||||
| CAS number | 9001-38-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a glucose-1-phosphatase (EC 3.1.3.10) is an enzyme that catalyzes the chemical reaction
- alpha-D-glucose 1-phosphate + H2O D-glucose + phosphate
Thus, the two substrates of this enzyme are alpha-D-glucose 1-phosphate and H2O, whereas its two products are D-glucose and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is alpha-D-glucose-1-phosphate phosphohydrolase. This enzyme participates in glycolysis / gluconeogenesis.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1NT4.
References
- FAULKNER P (1955). "A hexose-1-phosphatase in silkworm blood". Biochem. J. 60 (4): 590&ndash, 6. PMC 1216157. PMID 13249953.
- Turner DH; Turner JF (1960). "The hydrolysis of glucose monophosphates by a phosphatase preparation from pea seeds". Biochem. J. 74 (3): 486&ndash, 491. PMC 1204246. PMID 13839934.
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