Etoxeridine

Etoxeridine
Clinical data
Synonyms Etoxeridine, Carbetidine, Atenos
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
ECHA InfoCard 100.006.750 Edit this at Wikidata
Chemical and physical data
Formula C18H27NO4
Molar mass 321.41 g/mol
3D model (JSmol)
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Etoxeridine (Carbetidine, Atenos) is a 4-phenylpiperidine derivative that is related to the clinically used opioid analgesic drug pethidine (meperidine).

Etoxeridine was developed in the 1950s[1] and investigated for use in surgical anesthesia, however it was never commercialised and is not currently used in medicine.[2][3][4] As with other opioids which were not in clinical use during the drafting of the Controlled Substances Act, it is categorized as a Schedule I narcotic.

References

  1. BE Patent 558883
  2. Merlevede E, Levis S. Pharmacological study of carbetidine, a new synthetic analgesic. (French). Archives Internationales de Pharmacodynamie et de Thérapie. 1958 May 1;115(1-2):213-32.
  3. Sironi PG. Brief note on a new synthetic analgesic: carbetidine hydrochloride. (Italian). Minerva Anestesiologica. 1959 Jun;25(6):251-4.
  4. Crawford JS, Foldes FF. Studies on the respiratory and circulatory effects of carbetidine HCI used for supplementation of thiopentone sodium-nitrous oxide-oxygen anaesthesia. British Journal of Anaesthesia. 1959 Aug;31:348-51.


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