Cuevavirus

Cuevavirus
Virus classification
Group:	Group V ((−)ssRNA)
Order:	Mononegavirales
Family:	Filoviridae
Genus:	Cuevavirus
Type species
	Lloviu cuevavirus;

Cuevavirus is a genus in the family Filoviridae, which is included in the order Mononegavirales. Cuevavirus includes a single species, Lloviu cuevavirus, with one member, Lloviu virus (LLOV).^[1]^[2] It was discovered in the Cueva de Lloviu in Asturias, Spain, in a species of bats known as Schreiber's long-fingered bats (Miniopterus schreibersii).^[1] LLOV is a distant relative of the more widely known Ebola and Marburg viruses. Members of the genus are referred to as cuevaviruses. Cueva is derived from the Spanish word for cave.

Genus inclusion criteria

A virus that fulfills the criteria for being a member of the family Filoviridae is a member of the genus Cuevavirus if:^[1]

it is endemic in France, Portugal, or Spain
its fourth gene (GP) encodes four proteins (sGP, ssGP, Δ-peptide, and GP_1,2) using cotranscriptional editing to express ssGP and GP_1,2 and proteolytic cleavage to express sGP and Δ-peptide
its genome differs from that of Marburg virus (variant Musoke) by ≥50% and from that of Lloviu virus (variant Bat86) by <50% at the nucleotide level

References

1 2 3 Kuhn, J. H.; Becker, S.; Ebihara, H.; Geisbert, T. W.; Johnson, K. M.; Kawaoka, Y.; Lipkin, W. I.; Negredo, A. I.; Netesov, S. V.; Nichol, S. T.; Palacios, G.; Peters, C. J.; Tenorio, A.; Volchkov, V. E.; Jahrling, P. B. (2010). "Proposal for a revised taxonomy of the family Filoviridae: Classification, names of taxa and viruses, and virus abbreviations". Archives of Virology. 155 (12): 2083–2103. doi:10.1007/s00705-010-0814-x. PMC 3074192. PMID 21046175.
↑ Negredo, A.; Palacios, G.; Vázquez-Morón, S.; González, F. L.; Dopazo, H. N.; Molero, F.; Juste, J.; Quetglas, J.; Savji, N.; de la Cruz Martínez M; Herrera, J. E.; Pizarro, M.; Hutchison, S. K.; Echevarría, J. E.; Lipkin, W. I.; Tenorio, A. (2011). Basler, Christopher F, ed. "Discovery of an Ebolavirus-Like Filovirus in Europe". PLoS Pathogens. 7 (10): e1002304. doi:10.1371/journal.ppat.1002304. PMC 3197594. PMID 22039362.

External links

ViralZone: Cuevavirus

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[KuhnArch-1] 1 2 3 Kuhn, J. H.; Becker, S.; Ebihara, H.; Geisbert, T. W.; Johnson, K. M.; Kawaoka, Y.; Lipkin, W. I.; Negredo, A. I.; Netesov, S. V.; Nichol, S. T.; Palacios, G.; Peters, C. J.; Tenorio, A.; Volchkov, V. E.; Jahrling, P. B. (2010). "Proposal for a revised taxonomy of the family Filoviridae: Classification, names of taxa and viruses, and virus abbreviations". Archives of Virology. 155 (12): 2083–2103. doi:10.1007/s00705-010-0814-x. PMC 3074192. PMID 21046175.

[Negredo2011-2] Negredo, A.; Palacios, G.; Vázquez-Morón, S.; González, F. L.; Dopazo, H. N.; Molero, F.; Juste, J.; Quetglas, J.; Savji, N.; de la Cruz Martínez M; Herrera, J. E.; Pizarro, M.; Hutchison, S. K.; Echevarría, J. E.; Lipkin, W. I.; Tenorio, A. (2011). Basler, Christopher F, ed. "Discovery of an Ebolavirus-Like Filovirus in Europe". PLoS Pathogens. 7 (10): e1002304. doi:10.1371/journal.ppat.1002304. PMC 3197594. PMID 22039362.