Crocetin glucosyltransferase

Crocetin glucosyltransferase
Identifiers
EC number 2.4.1.271
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Crocetin glucosyltransferase (EC 2.4.1.271, crocetin GTase, UGTCs2) is an enzyme with systematic name UDP-glucose:crocetin 8-O-D-glucosyltransferase.[1][2] This enzyme catalyses the following chemical reaction

(1) UDP-glucose + crocetin UDP + beta-D-glucosyl crocetin
(2) UDP-glucose + beta-D-glucosyl crocetin UDP + bis(beta-D-glucosyl) crocetin
(3) UDP-glucose + beta-D-gentiobiosyl crocetin UDP + beta-D-gentiobiosyl beta-D-glucosyl crocetin

In Crocus sativus this enzyme esterifies a free carboxyl group of crocetin or crocetin glycosyl ester.

References

  1. Côté, F.; Cormier, F.; Dufresne, C.; Willemot, C. (2000). "Properties of a glucosyltransferase involved in crocin synthesis". Plant Sci. 153: 55–63. doi:10.1016/S0168-9452(99)00248-4.
  2. Moraga, A.R.; Nohales, P.F.; Perez, J.A.; Gomez-Gomez, L. (2004). "Glucosylation of the saffron apocarotenoid crocetin by a glucosyltransferase isolated from Crocus sativus stigmas". Planta. 219 (6): 955–966. doi:10.1007/s00425-004-1299-1. PMID 15605174.
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