UGT2B10

UGT2B10
Identifiers
AliasesUGT2B10, UDPGT2B10, UDP glucuronosyltransferase family 2 member B10
External IDsMGI: 2140962 HomoloGene: 117389 GeneCards: UGT2B10
Gene location (Human)
Chr.Chromosome 4 (human)[1]
Band4q13.2Start68,815,993 bp[1]
End68,831,196 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

7365

100727

Ensembl

ENSG00000275190
ENSG00000109181

ENSMUSG00000029260

UniProt

P36537

n/a

RefSeq (mRNA)

NM_001290091
NM_001075
NM_001144767

NM_153598

RefSeq (protein)

NP_001066
NP_001138239
NP_001277020

n/a

Location (UCSC)Chr 4: 68.82 – 68.83 MbChr 5: 86.89 – 86.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

UDP-glucuronosyltransferase 2B10 is an enzyme that in humans is encoded by the UGT2B10 gene.[5][6]

References

  1. 1 2 3 ENSG00000109181 GRCh38: Ensembl release 89: ENSG00000275190, ENSG00000109181 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029260 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Jin CJ, Miners JO, Lillywhite KJ, Mackenzie PI (Aug 1993). "cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily". Biochem Biophys Res Commun. 194 (1): 496–503. doi:10.1006/bbrc.1993.1847. PMID 8333863.
  6. ↑ "Entrez Gene: UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10".

Further reading

  • Chen G, Dellinger RW, Gallagher CJ, et al. (2008). "Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines". Pharmacogenet. Genomics. 18 (3): 181–91. doi:10.1097/FPC.0b013e3282f4dbdd. PMID 18300939.
  • Chen G, Blevins-Primeau AS, Dellinger RW, et al. (2007). "Glucuronidation of nicotine and cotinine by UGT2B10: loss of function by the UGT2B10 Codon 67 (Asp>Tyr) polymorphism". Cancer Res. 67 (19): 9024–9. doi:10.1158/0008-5472.CAN-07-2245. PMID 17909004.
  • Kaivosaari S, Toivonen P, Hesse LM, et al. (2007). "Nicotine glucuronidation and the human UDP-glucuronosyltransferase UGT2B10". Mol. Pharmacol. 72 (3): 761–8. doi:10.1124/mol.107.037093. PMID 17576790.
  • Liu T, Qian WJ, Gritsenko MA, et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMC 1850943. PMID 16335952.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Strassburg CP, Kneip S, Topp J, et al. (2000). "Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine". J. Biol. Chem. 275 (46): 36164–71. doi:10.1074/jbc.M002180200. PMID 10748067.
  • Strassburg CP, Strassburg A, Nguyen N, et al. (1999). "Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus". Biochem. J. 338 (2): 489–98. doi:10.1042/0264-6021:3380489. PMC 1220077. PMID 10024527.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.


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