ACER3

ACER3
Identifiers
AliasesACER3, APHC, PHCA, alkaline ceramidase 3, PLDECO
External IDsMGI: 1913440 HomoloGene: 5410 GeneCards: ACER3
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11q13.5Start76,860,867 bp[1]
End77,026,797 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

55331

66190

Ensembl

ENSG00000078124

ENSMUSG00000030760

UniProt

Q9NUN7

Q9D099

RefSeq (mRNA)

NM_001300953
NM_001300954
NM_001300955
NM_018367

NM_025408

RefSeq (protein)

NP_001287882
NP_001287883
NP_001287884
NP_060837

NP_079684
NP_001347544
NP_001347545
NP_001347546

Location (UCSC)Chr 11: 76.86 – 77.03 MbChr 7: 98.21 – 98.32 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Alkaline ceramidase 3 also known as ACER3 is a ceramidase enzyme which in humans is encoded by the ACER3 gene.[5][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000078124 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030760 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Mao C, Xu R, Szulc ZM, Bielawska A, Galadari SH, Obeid LM (July 2001). "Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide". J. Biol. Chem. 276 (28): 26577–88. doi:10.1074/jbc.M102818200. PMID 11356846.
  6. ↑ Mao C, Obeid LM (September 2008). "Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate". Biochim. Biophys. Acta. 1781 (9): 424–34. doi:10.1016/j.bbalip.2008.06.002. PMC 2614331. PMID 18619555.

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Wheeler HE, Metter EJ, Tanaka T, et al. (2009). Gibson G, ed. "Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging". PLoS Genet. 5 (10): e1000685. doi:10.1371/journal.pgen.1000685. PMC 2752811. PMID 19834535.
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