2-deoxyglucose-6-phosphatase

2-deoxyglucose-6-phosphatase
Identifiers
EC number 3.1.3.68
CAS number 65187-56-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a 2-deoxyglucose-6-phosphatase (EC 3.1.3.68) is an enzyme that catalyzes the chemical reaction

2-deoxy-D-glucose 6-phosphate + H2O 2-deoxy-D-glucose + phosphate

Thus, the two substrates of this enzyme are 2-deoxy-D-glucose 6-phosphate and H2O, whereas its two products are 2-deoxy-D-glucose and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 2-deoxy-D-glucose-6-phosphate phosphohydrolase. This enzyme is also called 2-deoxyglucose-6-phosphate phosphatase.

References

    • Favello A; Fulton L; Gattung S; et al. (1994). "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII". Science. 265 (5181): 2077–2082. doi:10.1126/science.8091229. PMID 8091229.
    • Randez-Gil F, Blasco A, Prieto JA, Sanz P (1995). "DOGR1 and DOGR2: two genes from Saccharomyces cerevisiae that confer 2-deoxyglucose resistance when overexpressed". Yeast. 11 (13): 1233–1240. doi:10.1002/yea.320111303. PMID 8553694.


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