CREB-bindingseiwit

Het CREB-bindingseiwit (CREB-Binding-Protein, afgekort CBP), is een co-activator bij de transcriptie.

Het CREB-bindingseiwit

Bij de mens wordt het CREB-bindingseiwit gecodeerd door het CREBBP-gen (ook wel CBP-gen genoemd).[1][2]

Het CREB-bindingseiwit heeft de volgende domeinen:

het nucleusreceptor interactie domein (RID),
het CREB en MYB interactie domein (KIX),
de cysteïne/histidine regio's (TAZ1/CH1 en TAZ2/CH3) en
het interferon reactiebindend domein (IBiD).

De CREB-bindingseiwit domeinen, KIX, TAZ1 en TAZ2 binden elk stevig aan de beide transactivatie domeinen 9aaTADs van de transcriptiefactor p53.[3][4]

Functie

Het CREBBP-gen is betrokken bij de transcriptionele coactivatie van veel verschillende transcriptiefactoren. Het werd voor het eerst geïsoleerd als een nucleuseiwit dat zich bindt aan het cAMP-reactie-elementbindend eiwit (CREB). Het gen speelt een kritische rol bij de embryonale ontwikkeling, controle van de groei en homeostase door te koppelen aan chromatine en het zo geschikt te maken voor de herkenning van de transcriptiefactor. Het door het gen gecodeerde eiwit heeft een eigen histon-acetyltransferase activiteit[5] en werkt ook ondersteunend voor het stabiliseren van bijkomende eiwitinteracties met het transcriptieomplex. Het eiwit acetyleert zowel histonen als non-histon eiwitten. Het eiwit heeft zeer sterk vergelijkbare regio's met het eiwit EP300 en hun bromodomein, cysteïne-histidine-rijke regio's en het histonacetyltransferasedomein.[6]

Klinisch belang

Mutaties in het CREBBP-gen is de oorzaak van het syndroom van Rubinstein-Taybi (RTS).[7] De chromosomale translocatie, waarbij het CREBBP-gen betrokken is, wordt in verband gebracht met acute myeloïde leukemie.[6][8]

Interacties

Het CREB-bindingseiwit vertoont interactie met de volgende eiwitten:

Activating transcription factor 2[9]
Androgen receptor[10][11][12][13]
Autoimmune regulator[14][15]
BRCA1[16][17][18][19][20]
BRCA2
C-jun[9]
C-src tyrosine kinase[21]
Casein kinase 2, alpha 1[22]
Ccaat-enhancer-binding proteins[23]
CDX2[24]
CREB1[9][10][25][26][27][28][29][30][31][32]
CSNK2A2[22]
CUTL1[33]
Cyclin-dependent kinase 8[34]

EBF1[35]
Estrogen receptor alpha[16][36]
EVI1[37]
FOXO1[38]
GLI3[39]
Glucocorticoid receptor[40]
Hepatocyte nuclear factor 4 alpha[41][42]
HIF1A[43][44][45]
HIPK2[46]
HNF1A[47]
HOXB7[48]
ING1[49]
KHDRBS1[50]
KLF13[51]

KLF4[52]
Ku70[53]
MAF[54]
MLL[31][55]
Mothers against decapentaplegic homolog 1[56][57]
MSX1[58]
MYB[28][59]
MYBL2[59]
MyoD[60][61]
NCOA6[62][63]
NEUROG1[57]
NFATC4[64]
NFE2[65]
NFE2L2[66]

Nuclear receptor coactivator 1[36][67]
Nuclear receptor coactivator 3[67][68]
NUP98[69]
P53[29][70][71]
PCAF[34][72]
POLR2A[34]
PPARGC1A[73]
Promyelocytic leukemia protein[74][75][76]
PTMA[77]
RBBP4[30]
RELA[13][78][79][80][81]
RPS6KA3[82]
SERTAD1[83]
Serum response factor[74]

SMARCB1[34]
SMARCA4[20][84]
SREBF1[85]
SREBF2[85]
SS18L1[86]
STAT1[87]
STAT2[88]
STAT6[89][90]
TCF3[91]
TGS1[92]
Thymine-DNA glycosylase[72]
Transcription Factor II B[16][72]
TRERF1[93]
Zif268.[94]

Bronnen, noten en/of referenties

Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, Goodman RH (October 1993). Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365 (6449): 855–9 . PMID: 8413673. DOI: 10.1038/365855a0.
Wydner KL, Bhattacharya S, Eckner R, Lawrence JB, Livingston DM (November 1995). Localization of human CREB-binding protein gene (CREBBP) to 16p13.2-p13.3 by fluorescence in situ hybridization. Genomics 30 (2): 395–6 . PMID: 8586450.
Teufel DP, Freund SM, Bycroft M, Fersht AR (April 2007). Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53. PNAS 104 (17): 7009–7014 . PMID: 17438265. PMC: 1855428. DOI: 10.1073/pnas.0702010104.; Piskacek S, Gregor M, Nemethova M, Grabner M, Kovarik P, Piskacek M (June 2007). Nine-amino-acid transactivation domain: establishment and prediction utilities. Genomics 89 (6): 756–68 . PMID: 17467953. DOI: 10.1016/j.ygeno.2007.02.003.; Piskacek M (2009-11-05) . 9aaTAD is a common transactivation domain recruits multiple general coactivators TAF9, MED15, CBP/p300 and GCN5. Nature Precedings Pre-publication . DOI: 10.1038/npre.2009.3488.2.; Piskacek M (2009-11-05) . 9aaTADs mimic DNA to interact with a pseudo-DNA Binding Domain KIX of Med15 (Molecular Chameleons). Nature Precedings Pre-publication . DOI: 10.1038/npre.2009.3939.1.; Piskacek M (2009-11-20) . 9aaTAD Prediction result (2006). Nature Precedings Pre-publication . DOI: 10.1038/npre.2009.3984.1.
The prediction for 9aaTADs (for both acidic and hydrophilic transactivation domains) is available online from ExPASy http://us.expasy.org/tools/ and EMBnet Spain https://archive.is/20130704002729/http://www.es.embnet.org/Services/EMBnetAT/htdoc/9aatad/
Ogryzko VV et al. "The transcriptional coactivators p300 and CBP are histone acetyltransferases". Cell. 1996 87(5):953-9.
Entrez Gene: CREBBP (CREB-binding protein).
Petrij F, Giles RH, Dauwerse HG, Saris JJ, Hennekam RC, Masuno M, Tommerup N, van Ommen GJ, Goodman RH, Peters DJ (July 1995). Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP. Nature 376 (6538): 348–51 . PMID: 7630403. DOI: 10.1038/376348a0.
Vizmanos JL, Larráyoz MJ, Lahortiga I, Floristán F, Alvarez C, Odero MD, Novo FJ, Calasanz MJ (April 2003). t(10;16)(q22;p13) and MORF-CREBBP fusion is a recurrent event in acute myeloid leukemia. Genes Chromosomes Cancer 36 (4): 402–5 . PMID: 12619164. DOI: 10.1002/gcc.10174.
Sano, Y, Tokitou F, Dai P, Maekawa T, Yamamoto T, Ishii S (Oct. 1998). CBP alleviates the intramolecular inhibition of ATF-2 function. J. Biol. Chem. 273 (44): 29098–105 (UNITED STATES). ISSN:0021-9258. PMID: 9786917. DOI: 10.1074/jbc.273.44.29098.
Kim, J, Jia L, Stallcup M R, Coetzee G A (Feb. 2005). The role of protein kinase A pathway and cAMP responsive element-binding protein in androgen receptor-mediated transcription at the prostate-specific antigen locus. J. Mol. Endocrinol. 34 (1): 107–18 (England). ISSN:0952-5041. PMID: 15691881. DOI: 10.1677/jme.1.01701.
Frønsdal, K, Engedal N, Slagsvold T, Saatcioglu F (Nov. 1998). CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1. J. Biol. Chem. 273 (48): 31853–9 (UNITED STATES). ISSN:0021-9258. PMID: 9822653. DOI: 10.1074/jbc.273.48.31853.
Ishitani, Ken, Yoshida Tasuku, Kitagawa Hirochika, Ohta Hiroaki, Nozawa Shiro, Kato Shigeaki (Jul. 2003). p54nrb acts as a transcriptional coactivator for activation function 1 of the human androgen receptor. Biochem. Biophys. Res. Commun. 306 (3): 660–5 (United States). ISSN:0006-291X. PMID: 12810069. DOI: 10.1016/S0006-291X(03)01021-0.
Aarnisalo, P, Palvimo J J, Jänne O A (Mar. 1998). CREB-binding protein in androgen receptor-mediated signaling. Proc. Natl. Acad. Sci. U.S.A. 95 (5): 2122–7 (UNITED STATES). ISSN:0027-8424. PMID: 9482849. PMC: 19270. DOI: 10.1073/pnas.95.5.2122.
Pitkänen, J, Doucas V, Sternsdorf T, Nakajima T, Aratani S, Jensen K, Will H, Vähämurto P, Ollila J, Vihinen M, Scott H S, Antonarakis S E, Kudoh J, Shimizu N, Krohn K, Peterson P (Jun. 2000). The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein. J. Biol. Chem. 275 (22): 16802–9 (UNITED STATES). ISSN:0021-9258. PMID: 10748110. DOI: 10.1074/jbc.M908944199.
Iioka, Takashi, Furukawa Keizo, Yamaguchi Akira, Shindo Hiroyuki, Yamashita Shunichi, Tsukazaki Tomoo (Aug. 2003). P300/CBP acts as a coactivator to cartilage homeoprotein-1 (Cart1), paired-like homeoprotein, through acetylation of the conserved lysine residue adjacent to the homeodomain. J. Bone Miner. Res. 18 (8): 1419–29 (United States). ISSN:0884-0431. PMID: 12929931. DOI: 10.1359/jbmr.2003.18.8.1419.
Fan, Saijun, Ma Yong Xian, Wang Chenguang, Yuan Ren-Qi, Meng Qinghui, Wang Ji-An, Erdos Michael, Goldberg Itzhak D, Webb Paul, Kushner Peter J, Pestell Richard G, Rosen Eliot M (Jan. 2002). p300 Modulates the BRCA1 inhibition of estrogen receptor activity. Cancer Res. 62 (1): 141–51 (United States). ISSN:0008-5472. PMID: 11782371.
Pao, G M, Janknecht R, Ruffner H, Hunter T, Verma I M (Feb. 2000). CBP/p300 interact with and function as transcriptional coactivators of BRCA1. Proc. Natl. Acad. Sci. U.S.A. 97 (3): 1020–5 (UNITED STATES). ISSN:0027-8424. PMID: 10655477. PMC: 15508. DOI: 10.1073/pnas.97.3.1020.
Chai, Y L, Cui J, Shao N, Shyam E, Reddy P, Rao V N (Jan. 1999). The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter. Oncogene 18 (1): 263–8 (ENGLAND). ISSN:0950-9232. PMID: 9926942. DOI: 10.1038/sj.onc.1202323.
Benezra, Miriam, Chevallier Nathalie, Morrison Debra J, MacLachlan Timothy K, El-Deiry Wafik S, Licht Jonathan D (Jul. 2003). BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65/RelA subunit. J. Biol. Chem. 278 (29): 26333–41 (United States). ISSN:0021-9258. PMID: 12700228. DOI: 10.1074/jbc.M303076200.
Neish, A S, Anderson S F, Schlegel B P, Wei W, Parvin J D (Feb. 1998). Factors associated with the mammalian RNA polymerase II holoenzyme. Nucleic Acids Res. 26 (3): 847–53 (ENGLAND). ISSN:0305-1048. PMID: 9443979. PMC: 147327. DOI: 10.1093/nar/26.3.847.
Kawabuchi, M, Satomi Y, Takao T, Shimonishi Y, Nada S, Nagai K, Tarakhovsky A, Okada M (Apr. 2000). Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases. Nature 404 (6781): 999–1003 (ENGLAND). ISSN:0028-0836. PMID: 10801129. DOI: 10.1038/35010121.
Yamaguchi, Y, Wada T, Suzuki F, Takagi T, Hasegawa J, Handa H (Aug. 1998). Casein kinase II interacts with the bZIP domains of several transcription factors. Nucleic Acids Res. 26 (16): 3854–61 (ENGLAND). ISSN:0305-1048. PMID: 9685505. PMC: 147779. DOI: 10.1093/nar/26.16.3854.
Kovacs KA, Steinmann M, Magistretti PJ, Halfon O, Cardinaux JR (Sept. 2003). CCAAT/enhancer-binding protein family members recruit the coactivator CREB-binding protein and trigger its phosphorylation. J Biol. Chem. 278 (38): 36959–65 (UNITED STATES). ISSN:0021-9258. PMID: 12857754. DOI: 10.1074/jbc.M303147200.
Lorentz, O, Suh E R, Taylor J K, Boudreau F, Traber P G (Mar. 1999). CREB-binding [corrected] protein interacts with the homeodomain protein Cdx2 and enhances transcriptional activity. J. Biol. Chem. 274 (11): 7196–9 (UNITED STATES). ISSN:0021-9258. PMID: 10066780. DOI: 10.1074/jbc.274.11.7196.
Shi, Yuling, Venkataraman Sujatha L, Dodson Gerald E, Mabb Angela M, LeBlanc Scott, Tibbetts Randal S (Apr. 2004). Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress. Proc. Natl. Acad. Sci. U.S.A. 101 (16): 5898–903 (United States). ISSN:0027-8424. PMID: 15073328. PMC: 395895. DOI: 10.1073/pnas.0307718101.
Shimomura, A, Ogawa Y, Kitani T, Fujisawa H, Hagiwara M (Jul. 1996). Calmodulin-dependent protein kinase II potentiates transcriptional activation through activating transcription factor 1 but not cAMP response element-binding protein. J. Biol. Chem. 271 (30): 17957–60 (UNITED STATES). ISSN:0021-9258. PMID: 8663317. DOI: 10.1074/jbc.271.30.17957.
Radhakrishnan, I, Pérez-Alvarado G C, Parker D, Dyson H J, Montminy M R, Wright P E (Dec. 1997). Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: a model for activator:coactivator interactions. Cell 91 (6): 741–52 (UNITED STATES). ISSN:0092-8674. PMID: 9413984. DOI: 10.1016/S0092-8674(00)80463-8.
Zor, Tsaffrir, Mayr Bernhard M, Dyson H Jane, Montminy Marc R, Wright Peter E (Nov. 2002). Roles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activators. J. Biol. Chem. 277 (44): 42241–8 (United States). ISSN:0021-9258. PMID: 12196545. DOI: 10.1074/jbc.M207361200.
Giebler, H A, Lemasson I, Nyborg J K (Jul. 2000). p53 recruitment of CREB binding protein mediated through phosphorylated CREB: a novel pathway of tumor suppressor regulation. Mol. Cell. Biol. 20 (13): 4849–58 (UNITED STATES). ISSN:0270-7306. PMID: 10848610. PMC: 85936. DOI: 10.1128/MCB.20.13.4849-4858.2000.
Zhang, Q, Vo N, Goodman R H (Jul. 2000). Histone binding protein RbAp48 interacts with a complex of CREB binding protein and phosphorylated CREB. Mol. Cell. Biol. 20 (14): 4970–8 (UNITED STATES). ISSN:0270-7306. PMID: 10866654. PMC: 85947. DOI: 10.1128/MCB.20.14.4970-4978.2000.
Ernst, P, Wang J, Huang M, Goodman R H, Korsmeyer S J (Apr. 2001). MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein. Mol. Cell. Biol. 21 (7): 2249–58 (United States). ISSN:0270-7306. PMID: 11259575. PMC: 86859. DOI: 10.1128/MCB.21.7.2249-2258.2001.
Ledo, Fran, Kremer Leonor, Mellström Britt, Naranjo Jose R (Sep. 2002). Ca2+-dependent block of CREB-CBP transcription by repressor DREAM. EMBO J. 21 (17): 4583–92 (England). ISSN:0261-4189. PMID: 12198160. PMC: 126180. DOI: 10.1093/emboj/cdf440.
Li, S, Aufiero B, Schiltz R L, Walsh M J (Jun. 2000). Regulation of the homeodomain CCAAT displacement/cut protein function by histone acetyltransferases p300/CREB-binding protein (CBP)-associated factor and CBP. Proc. Natl. Acad. Sci. U.S.A. 97 (13): 7166–71 (UNITED STATES). ISSN:0027-8424. PMID: 10852958. PMC: 16517. DOI: 10.1073/pnas.130028697.
Cho, H, Orphanides G, Sun X, Yang X J, Ogryzko V, Lees E, Nakatani Y, Reinberg D (Sep. 1998). A human RNA polymerase II complex containing factors that modify chromatin structure. Mol. Cell. Biol. 18 (9): 5355–63 (UNITED STATES). ISSN:0270-7306. PMID: 9710619. PMC: 109120.
Zhao, Fang, McCarrick-Walmsley Ruth, Akerblad Peter, Sigvardsson Mikael, Kadesch Tom (Jun. 2003). Inhibition of p300/CBP by early B-cell factor. Mol. Cell. Biol. 23 (11): 3837–46 (United States). ISSN:0270-7306. PMID: 12748286. PMC: 155219. DOI: 10.1128/MCB.23.11.3837-3846.2003.
Sheppard, H M, Harries J C, Hussain S, Bevan C, Heery D M (Jan. 2001). Analysis of the steroid receptor coactivator 1 (SRC1)-CREB binding protein interaction interface and its importance for the function of SRC1. Mol. Cell. Biol. 21 (1): 39–50 (UNITED STATES). ISSN:0270-7306. PMID: 11113179. PMC: 86566. DOI: 10.1128/MCB.21.1.39-50.2001.
Chakraborty, S, Senyuk V, Sitailo S, Chi Y, Nucifora G (Nov. 2001). Interaction of EVI1 with cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles. J. Biol. Chem. 276 (48): 44936–43 (United States). ISSN:0021-9258. PMID: 11568182. DOI: 10.1074/jbc.M106733200.
Nasrin, N, Ogg S, Cahill C M, Biggs W, Nui S, Dore J, Calvo D, Shi Y, Ruvkun G, Alexander-Bridges M C (Sep. 2000). DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells. Proc. Natl. Acad. Sci. U.S.A. 97 (19): 10412–7 (UNITED STATES). ISSN:0027-8424. PMID: 10973497. PMC: 27038. DOI: 10.1073/pnas.190326997.
Dai, P, Akimaru H, Tanaka Y, Maekawa T, Nakafuku M, Ishii S (Mar. 1999). Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3. J. Biol. Chem. 274 (12): 8143–52 (UNITED STATES). ISSN:0021-9258. PMID: 10075717. DOI: 10.1074/jbc.274.12.8143.
Almlöf, T, Wallberg A E, Gustafsson J A, Wright A P (Jun. 1998). Role of important hydrophobic amino acids in the interaction between the glucocorticoid receptor tau 1-core activation domain and target factors. Biochemistry 37 (26): 9586–94 (UNITED STATES). ISSN:0006-2960. PMID: 9649342. DOI: 10.1021/bi973029x.
Yoshida, E, Aratani S, Itou H, Miyagishi M, Takiguchi M, Osumu T, Murakami K, Fukamizu A (Dec. 1997). Functional association between CBP and HNF4 in trans-activation. Biochem. Biophys. Res. Commun. 241 (3): 664–9 (UNITED STATES). ISSN:0006-291X. PMID: 9434765. DOI: 10.1006/bbrc.1997.7871.
Dell, H, Hadzopoulou-Cladaras M (Mar. 1999). CREB-binding protein is a transcriptional coactivator for hepatocyte nuclear factor-4 and enhances apolipoprotein gene expression. J. Biol. Chem. 274 (13): 9013–21 (UNITED STATES). ISSN:0021-9258. PMID: 10085149. DOI: 10.1074/jbc.274.13.9013.
Ema, M, Hirota K, Mimura J, Abe H, Yodoi J, Sogawa K, Poellinger L, Fujii-Kuriyama Y (Apr. 1999). Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300. EMBO J. 18 (7): 1905–14 (ENGLAND). ISSN:0261-4189. PMID: 10202154. PMC: 1171276. DOI: 10.1093/emboj/18.7.1905.
Bhattacharya, S, Michels C L, Leung M K, Arany Z P, Kung A L, Livingston D M (Jan. 1999). Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1. Genes Dev. 13 (1): 64–75 (UNITED STATES). ISSN:0890-9369. PMID: 9887100. PMC: 316375. DOI: 10.1101/gad.13.1.64.
Park, Young-Kwon, Ahn Dae-Ro, Oh Myoungsuk, Lee Taekyoung, Yang Eun Gyeong, Son Miwon, Park Hyunsung (Jul. 2008). Nitric oxide donor, (+/-)-S-nitroso-N-acetylpenicillamine, stabilizes transactive hypoxia-inducible factor-1alpha by inhibiting von Hippel-Lindau recruitment and asparagine hydroxylation. Mol. Pharmacol. 74 (1): 236–45 (United States). PMID: 18426857. DOI: 10.1124/mol.108.045278.
Hofmann, Thomas G, Möller Andreas, Sirma Hüaeyin, Zentgraf Hanswalter, Taya Yoichi, Dröge Wulf, Will Hans, Schmitz M Lienhard (Jan. 2002). Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. Nat. Cell Biol. 4 (1): 1–10 (England). ISSN:1465-7392. PMID: 11740489. DOI: 10.1038/ncb715.
Soutoglou, E, Papafotiou G, Katrakili N, Talianidis I (Apr. 2000). Transcriptional activation by hepatocyte nuclear factor-1 requires synergism between multiple coactivator proteins. J. Biol. Chem. 275 (17): 12515–20 (UNITED STATES). ISSN:0021-9258. PMID: 10777539. DOI: 10.1074/jbc.275.17.12515.
Chariot, A, van Lint C, Chapelier M, Gielen J, Merville M P, Bours V (Jul. 1999). CBP and histone deacetylase inhibition enhance the transactivation potential of the HOXB7 homeodomain-containing protein. Oncogene 18 (27): 4007–14 (ENGLAND). ISSN:0950-9232. PMID: 10435624. DOI: 10.1038/sj.onc.1202776.
Vieyra, Diego, Loewith Robbie, Scott Michelle, Bonnefin Paul, Boisvert Francois-Michel, Cheema Parneet, Pastyryeva Svitlana, Meijer Maria, Johnston Randal N, Bazett-Jones David P, McMahon Steven, Cole Michael D, Young Dallan, Riabowol Karl (Aug. 2002). Human ING1 proteins differentially regulate histone acetylation. J. Biol. Chem. 277 (33): 29832–9 (United States). ISSN:0021-9258. PMID: 12015309. DOI: 10.1074/jbc.M200197200.
Hong, Wei, Resnick Ross J, Rakowski Carrie, Shalloway David, Taylor Steven J, Blobel Gerd A (Nov. 2002). Physical and functional interaction between the transcriptional cofactor CBP and the KH domain protein Sam68. Mol. Cancer Res. 1 (1): 48–55 (United States). ISSN:1541-7786. PMID: 12496368.
Song, Chao-Zhong, Keller Kimberly, Murata Ken, Asano Haruhiko, Stamatoyannopoulos George (Mar. 2002). Functional interaction between coactivators CBP/p300, PCAF, and transcription factor FKLF2. J. Biol. Chem. 277 (9): 7029–36 (United States). ISSN:0021-9258. PMID: 11748222. PMC: 2808425. DOI: 10.1074/jbc.M108826200.
Geiman, D E, Ton-That H, Johnson J M, Yang V W (Mar. 2000). Transactivation and growth suppression by the gut-enriched Krüppel-like factor (Krüppel-like factor 4) are dependent on acidic amino acid residues and protein-protein interaction. Nucleic Acids Res. 28 (5): 1106–13 (ENGLAND). PMID: 10666450. PMC: 102607. DOI: 10.1093/nar/28.5.1106.
Barlev, N A, Poltoratsky V, Owen-Hughes T, Ying C, Liu L, Workman J L, Berger S L (Mar. 1998). Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex. Mol. Cell. Biol. 18 (3): 1349–58 (UNITED STATES). ISSN:0270-7306. PMID: 9488450. PMC: 108848.
Chen, Qin, Dowhan Dennis H, Liang Dongcai, Moore David D, Overbeek Paul A (Jul. 2002). CREB-binding protein/p300 co-activation of crystallin gene expression. J. Biol. Chem. 277 (27): 24081–9 (United States). ISSN:0021-9258. PMID: 11943779. DOI: 10.1074/jbc.M201821200.
Goto, Natalie K, Zor Tsaffrir, Martinez-Yamout Maria, Dyson H Jane, Wright Peter E (Nov. 2002). Cooperativity in transcription factor binding to the coactivator CREB-binding protein (CBP). The mixed lineage leukemia protein (MLL) activation domain binds to an allosteric site on the KIX domain. J. Biol. Chem. 277 (45): 43168–74 (United States). ISSN:0021-9258. PMID: 12205094. DOI: 10.1074/jbc.M207660200.
Pearson, K L, Hunter T, Janknecht R (Dec. 1999). Activation of Smad1-mediated transcription by p300/CBP. Biochim. Biophys. Acta 1489 (2-3): 354–64 (NETHERLANDS). ISSN:0006-3002. PMID: 10673036. DOI: 10.1016/S0167-4781(99)00166-9.
Sun, Y, Nadal-Vicens M, Misono S, Lin M Z, Zubiaga A, Hua X, Fan G, Greenberg M E (Feb. 2001). Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell 104 (3): 365–76 (United States). ISSN:0092-8674. PMID: 11239394. DOI: 10.1016/S0092-8674(01)00224-0.
Shetty, S, Takahashi T, Matsui H, Ayengar R, Raghow R (May. 1999). Transcriptional autorepression of Msx1 gene is mediated by interactions of Msx1 protein with a multi-protein transcriptional complex containing TATA-binding protein, Sp1 and cAMP-response-element-binding protein-binding protein (CBP/p300). Biochem. J. 339 (3): 751–8 (ENGLAND). ISSN:0264-6021. PMID: 10215616. PMC: 1220213. DOI: 10.1042/0264-6021:3390751.
Bessa, M, Saville M K, Watson R J (Jun. 2001). Inhibition of cyclin A/Cdk2 phosphorylation impairs B-Myb transactivation function without affecting interactions with DNA or the CBP coactivator. Oncogene 20 (26): 3376–86 (England). ISSN:0950-9232. PMID: 11423988. DOI: 10.1038/sj.onc.1204439.
Polesskaya, A, Naguibneva I, Duquet A, Bengal E, Robin P, Harel-Bellan A (Aug. 2001). Interaction between acetylated MyoD and the bromodomain of CBP and/or p300. Mol. Cell. Biol. 21 (16): 5312–20 (United States). ISSN:0270-7306. PMID: 11463815. PMC: 87255. DOI: 10.1128/MCB.21.16.5312-5320.2001.
Sartorelli, V, Huang J, Hamamori Y, Kedes L (Feb. 1997). Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C. Mol. Cell. Biol. 17 (2): 1010–26 (UNITED STATES). ISSN:0270-7306. PMID: 9001254. PMC: 231826.
Lee, S K, Anzick S L, Choi J E, Bubendorf L, Guan X Y, Jung Y K, Kallioniemi O P, Kononen J, Trent J M, Azorsa D, Jhun B H, Cheong J H, Lee Y C, Meltzer P S, Lee J W (Nov. 1999). A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo. J. Biol. Chem. 274 (48): 34283–93 (UNITED STATES). ISSN:0021-9258. PMID: 10567404. DOI: 10.1074/jbc.274.48.34283.
Lee, S K, Jung S Y, Kim Y S, Na S Y, Lee Y C, Lee J W (Feb. 2001). Two distinct nuclear receptor-interaction domains and CREB-binding protein-dependent transactivation function of activating signal cointegrator-2. Mol. Endocrinol. 15 (2): 241–54 (United States). ISSN:0888-8809. PMID: 11158331. DOI: 10.1210/me.15.2.241.
Yang, T, Davis R J, Chow C W (Oct. 2001). Requirement of two NFATc4 transactivation domains for CBP potentiation. J. Biol. Chem. 276 (43): 39569–76 (United States). ISSN:0021-9258. PMID: 11514544. DOI: 10.1074/jbc.M102961200.
Hung, H L, Kim A Y, Hong W, Rakowski C, Blobel G A (Apr. 2001). Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation. J. Biol. Chem. 276 (14): 10715–21 (United States). ISSN:0021-9258. PMID: 11154691. DOI: 10.1074/jbc.M007846200.
Katoh, Y, Itoh K, Yoshida E, Miyagishi M, Fukamizu A, Yamamoto M (Oct. 2001). Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription. Genes Cells 6 (10): 857–68 (England). ISSN:1356-9597. PMID: 11683914. DOI: 10.1046/j.1365-2443.2001.00469.x.
Wu, Ray-Chang, Qin Jun, Hashimoto Yoshihiro, Wong Jiemin, Xu Jianming, Tsai Sophia Y, Tsai Ming-Jer, O'Malley Bert W (May. 2002). Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol. Cell. Biol. 22 (10): 3549–61 (United States). ISSN:0270-7306. PMID: 11971985. PMC: 133790. DOI: 10.1128/MCB.22.10.3549-3561.2002.
Naltner, A, Wert S, Whitsett J A, Yan C (Dec. 2000). Temporal/spatial expression of nuclear receptor coactivators in the mouse lung. Am. J. Physiol. Lung Cell Mol. Physiol. 279 (6): L1066–74 (UNITED STATES). ISSN:1040-0605. PMID: 11076796.
Kasper, L H, Brindle P K, Schnabel C A, Pritchard C E, Cleary M L, van Deursen J M (Jan. 1999). CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity. Mol. Cell. Biol. 19 (1): 764–76 (UNITED STATES). ISSN:0270-7306. PMID: 9858599. PMC: 83933.
Ito, Akihiro, Kawaguchi Yoshiharu, Lai Chun-Hsiang, Kovacs Jeffrey J, Higashimoto Yuichiro, Appella Ettore, Yao Tso-Pang (Nov. 2002). MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation. EMBO J. 21 (22): 6236–45 (England). ISSN:0261-4189. PMID: 12426395. PMC: 137207. DOI: 10.1093/emboj/cdf616.
Livengood, Jill A, Scoggin Kirsten E S, Van Orden Karen, McBryant Steven J, Edayathumangalam Rajeswari S, Laybourn Paul J, Nyborg Jennifer K (Mar. 2002). p53 Transcriptional activity is mediated through the SRC1-interacting domain of CBP/p300. J. Biol. Chem. 277 (11): 9054–61 (United States). ISSN:0021-9258. PMID: 11782467. DOI: 10.1074/jbc.M108870200.
Tini, Marc, Benecke Arndt, Um Soo-Joong, Torchia Joseph, Evans Ronald M, Chambon Pierre (Feb. 2002). Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription. Mol. Cell 9 (2): 265–77 (United States). ISSN:1097-2765. PMID: 11864601. DOI: 10.1016/S1097-2765(02)00453-7.
Puigserver, P, Adelmant G, Wu Z, Fan M, Xu J, O'Malley B, Spiegelman B M (Nov. 1999). Activation of PPARgamma coactivator-1 through transcription factor docking. Science 286 (5443): 1368–71 (UNITED STATES). ISSN:0036-8075. PMID: 10558993. DOI: 10.1126/science.286.5443.1368.
Matsuzaki, Kazuhito, Minami Takeshi, Tojo Masahide, Honda Yoshiomi, Saitoh Noriko, Nagahiro Shinji, Saya Hideyuki, Nakao Mitsuyoshi (Mar. 2003). PML-nuclear bodies are involved in cellular serum response. Genes Cells 8 (3): 275–86 (England). ISSN:1356-9597. PMID: 12622724. DOI: 10.1046/j.1365-2443.2003.00632.x.
Doucas, V, Tini M, Egan D A, Evans R M (Mar. 1999). Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling. Proc. Natl. Acad. Sci. U.S.A. 96 (6): 2627–32 (UNITED STATES). ISSN:0027-8424. PMID: 10077561. PMC: 15819. DOI: 10.1073/pnas.96.6.2627.
Zhong, S, Delva L, Rachez C, Cenciarelli C, Gandini D, Zhang H, Kalantry S, Freedman L P, Pandolfi P P (Nov. 1999). A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteins. Nat. Genet. 23 (3): 287–95 (UNITED STATES). ISSN:1061-4036. PMID: 10610177. DOI: 10.1038/15463.
Karetsou, Zoe, Kretsovali Adroniki, Murphy Carol, Tsolas Orestes, Papamarcaki Thomais (Apr. 2002). Prothymosin alpha interacts with the CREB-binding protein and potentiates transcription. EMBO Rep. 3 (4): 361–6 (England). ISSN:1469-221X. PMID: 11897665. PMC: 1084059. DOI: 10.1093/embo-reports/kvf071.
Jang, Hyun Duk, Yoon Kwiyeom, Shin Young Joo, Kim Jaesang, Lee Soo Young (Jun. 2004). PIAS3 suppresses NF-kappaB-mediated transcription by interacting with the p65/RelA subunit. J. Biol. Chem. 279 (23): 24873–80 (United States). ISSN:0021-9258. PMID: 15140884. DOI: 10.1074/jbc.M313018200.
Zhong, Haihong, May Michael J, Jimi Eijiro, Ghosh Sankar (Mar. 2002). The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol. Cell 9 (3): 625–36 (United States). ISSN:1097-2765. PMID: 11931769. DOI: 10.1016/S1097-2765(02)00477-X.
Parry, G C, Mackman N (Dec. 1997). Role of cyclic AMP response element-binding protein in cyclic AMP inhibition of NF-kappaB-mediated transcription. J. Immunol. 159 (11): 5450–6 (UNITED STATES). ISSN:0022-1767. PMID: 9548485.
Gerritsen, M E, Williams A J, Neish A S, Moore S, Shi Y, Collins T (Apr. 1997). CREB-binding protein/p300 are transcriptional coactivators of p65. Proc. Natl. Acad. Sci. U.S.A. 94 (7): 2927–32 (UNITED STATES). ISSN:0027-8424. PMID: 9096323. PMC: 20299. DOI: 10.1073/pnas.94.7.2927.
Merienne, K, Pannetier S, Harel-Bellan A, Sassone-Corsi P (Oct. 2001). Mitogen-regulated RSK2-CBP interaction controls their kinase and acetylase activities. Mol. Cell. Biol. 21 (20): 7089–96 (United States). ISSN:0270-7306. PMID: 11564891. PMC: 99884. DOI: 10.1128/MCB.21.20.7089-7096.2001.
Hirose, Takuji, Fujii Ryouji, Nakamura Hiroshi, Aratani Satoko, Fujita Hidetoshi, Nakazawa Minako, Nakamura Kohzo, Nishioka Kusuki, Nakajima Toshihiro (Jun. 2003). Regulation of CREB-mediated transcription by association of CDK4 binding protein p34SEI-1 with CBP. Int. J. Mol. Med. 11 (6): 705–12 (Greece). ISSN:1107-3756. PMID: 12736710.
DiRenzo, J, Shang Y, Phelan M, Sif S, Myers M, Kingston R, Brown M (Oct. 2000). BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation. Mol. Cell. Biol. 20 (20): 7541–9 (UNITED STATES). ISSN:0270-7306. PMID: 11003650. PMC: 86306. DOI: 10.1128/MCB.20.20.7541-7549.2000.
Oliner, J D, Andresen J M, Hansen S K, Zhou S, Tjian R (Nov. 1996). SREBP transcriptional activity is mediated through an interaction with the CREB-binding protein. Genes Dev. 10 (22): 2903–11 (UNITED STATES). ISSN:0890-9369. PMID: 8918891. DOI: 10.1101/gad.10.22.2903.
Aizawa, Hiroyuki, Hu Shu-Ching, Bobb Kathryn, Balakrishnan Karthik, Ince Gulayse, Gurevich Inga, Cowan Mitra, Ghosh Anirvan (Jan. 2004). Dendrite development regulated by CREST, a calcium-regulated transcriptional activator. Science 303 (5655): 197–202 (United States). PMID: 14716005. DOI: 10.1126/science.1089845.
Zhang, J J, Vinkemeier U, Gu W, Chakravarti D, Horvath C M, Darnell J E (Dec. 1996). Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling. Proc. Natl. Acad. Sci. U.S.A. 93 (26): 15092–6 (UNITED STATES). ISSN:0027-8424. PMID: 8986769. PMC: 26361. DOI: 10.1073/pnas.93.26.15092.
Bhattacharya, S, Eckner R, Grossman S, Oldread E, Arany Z, D'Andrea A, Livingston D M (Sep. 1996). Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha. Nature 383 (6598): 344–7 (ENGLAND). ISSN:0028-0836. PMID: 8848048. DOI: 10.1038/383344a0.
Litterst, C M, Pfitzner E (Dec. 2001). Transcriptional activation by STAT6 requires the direct interaction with NCoA-1. J. Biol. Chem. 276 (49): 45713–21 (United States). ISSN:0021-9258. PMID: 11574547. DOI: 10.1074/jbc.M108132200.
McDonald, C, Reich N C (Jul. 1999). Cooperation of the transcriptional coactivators CBP and p300 with Stat6. J. Interferon Cytokine Res. 19 (7): 711–22 (UNITED STATES). ISSN:1079-9907. PMID: 10454341. DOI: 10.1089/107999099313550.
Bradney, Curtis, Hjelmeland Mark, Komatsu Yasuhiko, Yoshida Minoru, Yao Tso-Pang, Zhuang Yuan (Jan. 2003). Regulation of E2A activities by histone acetyltransferases in B lymphocyte development. J. Biol. Chem. 278 (4): 2370–6 (United States). ISSN:0021-9258. PMID: 12435739. DOI: 10.1074/jbc.M211464200.
Misra, Parimal, Qi Chao, Yu Songtao, Shah Sejal H, Cao Wen-Qing, Rao M Sambasiva, Thimmapaya Bayar, Zhu Yijun, Reddy Janardan K (May. 2002). Interaction of PIMT with transcriptional coactivators CBP, p300, and PBP differential role in transcriptional regulation. J. Biol. Chem. 277 (22): 20011–9 (United States). ISSN:0021-9258. PMID: 11912212. DOI: 10.1074/jbc.M201739200.
Gizard, F, Lavallée B, DeWitte F, Hum D W (Sep. 2001). A novel zinc finger protein TReP-132 interacts with CBP/p300 to regulate human CYP11A1 gene expression. J. Biol. Chem. 276 (36): 33881–92 (United States). ISSN:0021-9258. PMID: 11349124. DOI: 10.1074/jbc.M100113200.
Silverman, E S, Du J, Williams A J, Wadgaonkar R, Drazen J M, Collins T (Nov. 1998). cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1). Biochem. J. 336 (1): 183–9 (ENGLAND). ISSN:0264-6021. PMID: 9806899. PMC: 1219856.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[pmid8413673-1] Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, Goodman RH (October 1993). Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365 (6449): 855–9 . PMID: 8413673. DOI: 10.1038/365855a0.

[pmid8586450-2] Wydner KL, Bhattacharya S, Eckner R, Lawrence JB, Livingston DM (November 1995). Localization of human CREB-binding protein gene (CREBBP) to 16p13.2-p13.3 by fluorescence in situ hybridization. Genomics 30 (2): 395–6 . PMID: 8586450.

[3] Teufel DP, Freund SM, Bycroft M, Fersht AR (April 2007). Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53. PNAS 104 (17): 7009–7014 . PMID: 17438265. PMC: 1855428. DOI: 10.1073/pnas.0702010104.; Piskacek S, Gregor M, Nemethova M, Grabner M, Kovarik P, Piskacek M (June 2007). Nine-amino-acid transactivation domain: establishment and prediction utilities. Genomics 89 (6): 756–68 . PMID: 17467953. DOI: 10.1016/j.ygeno.2007.02.003.; Piskacek M (2009-11-05) . 9aaTAD is a common transactivation domain recruits multiple general coactivators TAF9, MED15, CBP/p300 and GCN5. Nature Precedings Pre-publication . DOI: 10.1038/npre.2009.3488.2.; Piskacek M (2009-11-05) . 9aaTADs mimic DNA to interact with a pseudo-DNA Binding Domain KIX of Med15 (Molecular Chameleons). Nature Precedings Pre-publication . DOI: 10.1038/npre.2009.3939.1.; Piskacek M (2009-11-20) . 9aaTAD Prediction result (2006). Nature Precedings Pre-publication . DOI: 10.1038/npre.2009.3984.1.

[4] The prediction for 9aaTADs (for both acidic and hydrophilic transactivation domains) is available online from ExPASy http://us.expasy.org/tools/ and EMBnet Spain https://archive.is/20130704002729/http://www.es.embnet.org/Services/EMBnetAT/htdoc/9aatad/

[5] Ogryzko VV et al. "The transcriptional coactivators p300 and CBP are histone acetyltransferases". Cell. 1996 87(5):953-9.

[entrez-6] Entrez Gene: CREBBP (CREB-binding protein).

[pmid7630403-7] Petrij F, Giles RH, Dauwerse HG, Saris JJ, Hennekam RC, Masuno M, Tommerup N, van Ommen GJ, Goodman RH, Peters DJ (July 1995). Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP. Nature 376 (6538): 348–51 . PMID: 7630403. DOI: 10.1038/376348a0.

[pmid12619164-8] Vizmanos JL, Larráyoz MJ, Lahortiga I, Floristán F, Alvarez C, Odero MD, Novo FJ, Calasanz MJ (April 2003). t(10;16)(q22;p13) and MORF-CREBBP fusion is a recurrent event in acute myeloid leukemia. Genes Chromosomes Cancer 36 (4): 402–5 . PMID: 12619164. DOI: 10.1002/gcc.10174.

[pmid9786917-9] Sano, Y, Tokitou F, Dai P, Maekawa T, Yamamoto T, Ishii S (Oct. 1998). CBP alleviates the intramolecular inhibition of ATF-2 function. J. Biol. Chem. 273 (44): 29098–105 (UNITED STATES). ISSN:0021-9258. PMID: 9786917. DOI: 10.1074/jbc.273.44.29098.

[pmid15691881-10] Kim, J, Jia L, Stallcup M R, Coetzee G A (Feb. 2005). The role of protein kinase A pathway and cAMP responsive element-binding protein in androgen receptor-mediated transcription at the prostate-specific antigen locus. J. Mol. Endocrinol. 34 (1): 107–18 (England). ISSN:0952-5041. PMID: 15691881. DOI: 10.1677/jme.1.01701.

[pmid9822653-11] Frønsdal, K, Engedal N, Slagsvold T, Saatcioglu F (Nov. 1998). CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1. J. Biol. Chem. 273 (48): 31853–9 (UNITED STATES). ISSN:0021-9258. PMID: 9822653. DOI: 10.1074/jbc.273.48.31853.

[pmid12810069-12] Ishitani, Ken, Yoshida Tasuku, Kitagawa Hirochika, Ohta Hiroaki, Nozawa Shiro, Kato Shigeaki (Jul. 2003). p54nrb acts as a transcriptional coactivator for activation function 1 of the human androgen receptor. Biochem. Biophys. Res. Commun. 306 (3): 660–5 (United States). ISSN:0006-291X. PMID: 12810069. DOI: 10.1016/S0006-291X(03)01021-0.

[pmid9482849-13] Aarnisalo, P, Palvimo J J, Jänne O A (Mar. 1998). CREB-binding protein in androgen receptor-mediated signaling. Proc. Natl. Acad. Sci. U.S.A. 95 (5): 2122–7 (UNITED STATES). ISSN:0027-8424. PMID: 9482849. PMC: 19270. DOI: 10.1073/pnas.95.5.2122.

[pmid10748110-14] Pitkänen, J, Doucas V, Sternsdorf T, Nakajima T, Aratani S, Jensen K, Will H, Vähämurto P, Ollila J, Vihinen M, Scott H S, Antonarakis S E, Kudoh J, Shimizu N, Krohn K, Peterson P (Jun. 2000). The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein. J. Biol. Chem. 275 (22): 16802–9 (UNITED STATES). ISSN:0021-9258. PMID: 10748110. DOI: 10.1074/jbc.M908944199.

[pmid12929931-15] Iioka, Takashi, Furukawa Keizo, Yamaguchi Akira, Shindo Hiroyuki, Yamashita Shunichi, Tsukazaki Tomoo (Aug. 2003). P300/CBP acts as a coactivator to cartilage homeoprotein-1 (Cart1), paired-like homeoprotein, through acetylation of the conserved lysine residue adjacent to the homeodomain. J. Bone Miner. Res. 18 (8): 1419–29 (United States). ISSN:0884-0431. PMID: 12929931. DOI: 10.1359/jbmr.2003.18.8.1419.

[pmid11782371-16] Fan, Saijun, Ma Yong Xian, Wang Chenguang, Yuan Ren-Qi, Meng Qinghui, Wang Ji-An, Erdos Michael, Goldberg Itzhak D, Webb Paul, Kushner Peter J, Pestell Richard G, Rosen Eliot M (Jan. 2002). p300 Modulates the BRCA1 inhibition of estrogen receptor activity. Cancer Res. 62 (1): 141–51 (United States). ISSN:0008-5472. PMID: 11782371.

[pmid10655477-17] Pao, G M, Janknecht R, Ruffner H, Hunter T, Verma I M (Feb. 2000). CBP/p300 interact with and function as transcriptional coactivators of BRCA1. Proc. Natl. Acad. Sci. U.S.A. 97 (3): 1020–5 (UNITED STATES). ISSN:0027-8424. PMID: 10655477. PMC: 15508. DOI: 10.1073/pnas.97.3.1020.

[pmid9926942-18] Chai, Y L, Cui J, Shao N, Shyam E, Reddy P, Rao V N (Jan. 1999). The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter. Oncogene 18 (1): 263–8 (ENGLAND). ISSN:0950-9232. PMID: 9926942. DOI: 10.1038/sj.onc.1202323.

[pmid12700228-19] Benezra, Miriam, Chevallier Nathalie, Morrison Debra J, MacLachlan Timothy K, El-Deiry Wafik S, Licht Jonathan D (Jul. 2003). BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65/RelA subunit. J. Biol. Chem. 278 (29): 26333–41 (United States). ISSN:0021-9258. PMID: 12700228. DOI: 10.1074/jbc.M303076200.

[pmid9443979-20] Neish, A S, Anderson S F, Schlegel B P, Wei W, Parvin J D (Feb. 1998). Factors associated with the mammalian RNA polymerase II holoenzyme. Nucleic Acids Res. 26 (3): 847–53 (ENGLAND). ISSN:0305-1048. PMID: 9443979. PMC: 147327. DOI: 10.1093/nar/26.3.847.

[pmid10801129-21] Kawabuchi, M, Satomi Y, Takao T, Shimonishi Y, Nada S, Nagai K, Tarakhovsky A, Okada M (Apr. 2000). Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases. Nature 404 (6781): 999–1003 (ENGLAND). ISSN:0028-0836. PMID: 10801129. DOI: 10.1038/35010121.

[pmid9685505-22] Yamaguchi, Y, Wada T, Suzuki F, Takagi T, Hasegawa J, Handa H (Aug. 1998). Casein kinase II interacts with the bZIP domains of several transcription factors. Nucleic Acids Res. 26 (16): 3854–61 (ENGLAND). ISSN:0305-1048. PMID: 9685505. PMC: 147779. DOI: 10.1093/nar/26.16.3854.

[pmid12857754-23] Kovacs KA, Steinmann M, Magistretti PJ, Halfon O, Cardinaux JR (Sept. 2003). CCAAT/enhancer-binding protein family members recruit the coactivator CREB-binding protein and trigger its phosphorylation. J Biol. Chem. 278 (38): 36959–65 (UNITED STATES). ISSN:0021-9258. PMID: 12857754. DOI: 10.1074/jbc.M303147200.

[pmid10066780-24] Lorentz, O, Suh E R, Taylor J K, Boudreau F, Traber P G (Mar. 1999). CREB-binding [corrected] protein interacts with the homeodomain protein Cdx2 and enhances transcriptional activity. J. Biol. Chem. 274 (11): 7196–9 (UNITED STATES). ISSN:0021-9258. PMID: 10066780. DOI: 10.1074/jbc.274.11.7196.

[pmid15073328-25] Shi, Yuling, Venkataraman Sujatha L, Dodson Gerald E, Mabb Angela M, LeBlanc Scott, Tibbetts Randal S (Apr. 2004). Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress. Proc. Natl. Acad. Sci. U.S.A. 101 (16): 5898–903 (United States). ISSN:0027-8424. PMID: 15073328. PMC: 395895. DOI: 10.1073/pnas.0307718101.

[pmid8663317-26] Shimomura, A, Ogawa Y, Kitani T, Fujisawa H, Hagiwara M (Jul. 1996). Calmodulin-dependent protein kinase II potentiates transcriptional activation through activating transcription factor 1 but not cAMP response element-binding protein. J. Biol. Chem. 271 (30): 17957–60 (UNITED STATES). ISSN:0021-9258. PMID: 8663317. DOI: 10.1074/jbc.271.30.17957.

[pmid9413984-27] Radhakrishnan, I, Pérez-Alvarado G C, Parker D, Dyson H J, Montminy M R, Wright P E (Dec. 1997). Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: a model for activator:coactivator interactions. Cell 91 (6): 741–52 (UNITED STATES). ISSN:0092-8674. PMID: 9413984. DOI: 10.1016/S0092-8674(00)80463-8.

[pmid12196545-28] Zor, Tsaffrir, Mayr Bernhard M, Dyson H Jane, Montminy Marc R, Wright Peter E (Nov. 2002). Roles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activators. J. Biol. Chem. 277 (44): 42241–8 (United States). ISSN:0021-9258. PMID: 12196545. DOI: 10.1074/jbc.M207361200.

[pmid10848610-29] Giebler, H A, Lemasson I, Nyborg J K (Jul. 2000). p53 recruitment of CREB binding protein mediated through phosphorylated CREB: a novel pathway of tumor suppressor regulation. Mol. Cell. Biol. 20 (13): 4849–58 (UNITED STATES). ISSN:0270-7306. PMID: 10848610. PMC: 85936. DOI: 10.1128/MCB.20.13.4849-4858.2000.

[pmid10866654-30] Zhang, Q, Vo N, Goodman R H (Jul. 2000). Histone binding protein RbAp48 interacts with a complex of CREB binding protein and phosphorylated CREB. Mol. Cell. Biol. 20 (14): 4970–8 (UNITED STATES). ISSN:0270-7306. PMID: 10866654. PMC: 85947. DOI: 10.1128/MCB.20.14.4970-4978.2000.

[pmid11259575-31] Ernst, P, Wang J, Huang M, Goodman R H, Korsmeyer S J (Apr. 2001). MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein. Mol. Cell. Biol. 21 (7): 2249–58 (United States). ISSN:0270-7306. PMID: 11259575. PMC: 86859. DOI: 10.1128/MCB.21.7.2249-2258.2001.

[pmid12198160-32] Ledo, Fran, Kremer Leonor, Mellström Britt, Naranjo Jose R (Sep. 2002). Ca2+-dependent block of CREB-CBP transcription by repressor DREAM. EMBO J. 21 (17): 4583–92 (England). ISSN:0261-4189. PMID: 12198160. PMC: 126180. DOI: 10.1093/emboj/cdf440.

[pmid10852958-33] Li, S, Aufiero B, Schiltz R L, Walsh M J (Jun. 2000). Regulation of the homeodomain CCAAT displacement/cut protein function by histone acetyltransferases p300/CREB-binding protein (CBP)-associated factor and CBP. Proc. Natl. Acad. Sci. U.S.A. 97 (13): 7166–71 (UNITED STATES). ISSN:0027-8424. PMID: 10852958. PMC: 16517. DOI: 10.1073/pnas.130028697.

[pmid9710619-34] Cho, H, Orphanides G, Sun X, Yang X J, Ogryzko V, Lees E, Nakatani Y, Reinberg D (Sep. 1998). A human RNA polymerase II complex containing factors that modify chromatin structure. Mol. Cell. Biol. 18 (9): 5355–63 (UNITED STATES). ISSN:0270-7306. PMID: 9710619. PMC: 109120.

[pmid12748286-35] Zhao, Fang, McCarrick-Walmsley Ruth, Akerblad Peter, Sigvardsson Mikael, Kadesch Tom (Jun. 2003). Inhibition of p300/CBP by early B-cell factor. Mol. Cell. Biol. 23 (11): 3837–46 (United States). ISSN:0270-7306. PMID: 12748286. PMC: 155219. DOI: 10.1128/MCB.23.11.3837-3846.2003.

[pmid11113179-36] Sheppard, H M, Harries J C, Hussain S, Bevan C, Heery D M (Jan. 2001). Analysis of the steroid receptor coactivator 1 (SRC1)-CREB binding protein interaction interface and its importance for the function of SRC1. Mol. Cell. Biol. 21 (1): 39–50 (UNITED STATES). ISSN:0270-7306. PMID: 11113179. PMC: 86566. DOI: 10.1128/MCB.21.1.39-50.2001.

[pmid11568182-37] Chakraborty, S, Senyuk V, Sitailo S, Chi Y, Nucifora G (Nov. 2001). Interaction of EVI1 with cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles. J. Biol. Chem. 276 (48): 44936–43 (United States). ISSN:0021-9258. PMID: 11568182. DOI: 10.1074/jbc.M106733200.

[pmid10973497-38] Nasrin, N, Ogg S, Cahill C M, Biggs W, Nui S, Dore J, Calvo D, Shi Y, Ruvkun G, Alexander-Bridges M C (Sep. 2000). DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells. Proc. Natl. Acad. Sci. U.S.A. 97 (19): 10412–7 (UNITED STATES). ISSN:0027-8424. PMID: 10973497. PMC: 27038. DOI: 10.1073/pnas.190326997.

[pmid10075717-39] Dai, P, Akimaru H, Tanaka Y, Maekawa T, Nakafuku M, Ishii S (Mar. 1999). Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3. J. Biol. Chem. 274 (12): 8143–52 (UNITED STATES). ISSN:0021-9258. PMID: 10075717. DOI: 10.1074/jbc.274.12.8143.

[pmid9649342-40] Almlöf, T, Wallberg A E, Gustafsson J A, Wright A P (Jun. 1998). Role of important hydrophobic amino acids in the interaction between the glucocorticoid receptor tau 1-core activation domain and target factors. Biochemistry 37 (26): 9586–94 (UNITED STATES). ISSN:0006-2960. PMID: 9649342. DOI: 10.1021/bi973029x.

[pmid9434765-41] Yoshida, E, Aratani S, Itou H, Miyagishi M, Takiguchi M, Osumu T, Murakami K, Fukamizu A (Dec. 1997). Functional association between CBP and HNF4 in trans-activation. Biochem. Biophys. Res. Commun. 241 (3): 664–9 (UNITED STATES). ISSN:0006-291X. PMID: 9434765. DOI: 10.1006/bbrc.1997.7871.

[pmid10085149-42] Dell, H, Hadzopoulou-Cladaras M (Mar. 1999). CREB-binding protein is a transcriptional coactivator for hepatocyte nuclear factor-4 and enhances apolipoprotein gene expression. J. Biol. Chem. 274 (13): 9013–21 (UNITED STATES). ISSN:0021-9258. PMID: 10085149. DOI: 10.1074/jbc.274.13.9013.

[pmid10202154-43] Ema, M, Hirota K, Mimura J, Abe H, Yodoi J, Sogawa K, Poellinger L, Fujii-Kuriyama Y (Apr. 1999). Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300. EMBO J. 18 (7): 1905–14 (ENGLAND). ISSN:0261-4189. PMID: 10202154. PMC: 1171276. DOI: 10.1093/emboj/18.7.1905.

[pmid9887100-44] Bhattacharya, S, Michels C L, Leung M K, Arany Z P, Kung A L, Livingston D M (Jan. 1999). Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1. Genes Dev. 13 (1): 64–75 (UNITED STATES). ISSN:0890-9369. PMID: 9887100. PMC: 316375. DOI: 10.1101/gad.13.1.64.

[pmid18426857-45] Park, Young-Kwon, Ahn Dae-Ro, Oh Myoungsuk, Lee Taekyoung, Yang Eun Gyeong, Son Miwon, Park Hyunsung (Jul. 2008). Nitric oxide donor, (+/-)-S-nitroso-N-acetylpenicillamine, stabilizes transactive hypoxia-inducible factor-1alpha by inhibiting von Hippel-Lindau recruitment and asparagine hydroxylation. Mol. Pharmacol. 74 (1): 236–45 (United States). PMID: 18426857. DOI: 10.1124/mol.108.045278.

[pmid11740489-46] Hofmann, Thomas G, Möller Andreas, Sirma Hüaeyin, Zentgraf Hanswalter, Taya Yoichi, Dröge Wulf, Will Hans, Schmitz M Lienhard (Jan. 2002). Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. Nat. Cell Biol. 4 (1): 1–10 (England). ISSN:1465-7392. PMID: 11740489. DOI: 10.1038/ncb715.

[pmid10777539-47] Soutoglou, E, Papafotiou G, Katrakili N, Talianidis I (Apr. 2000). Transcriptional activation by hepatocyte nuclear factor-1 requires synergism between multiple coactivator proteins. J. Biol. Chem. 275 (17): 12515–20 (UNITED STATES). ISSN:0021-9258. PMID: 10777539. DOI: 10.1074/jbc.275.17.12515.

[pmid10435624-48] Chariot, A, van Lint C, Chapelier M, Gielen J, Merville M P, Bours V (Jul. 1999). CBP and histone deacetylase inhibition enhance the transactivation potential of the HOXB7 homeodomain-containing protein. Oncogene 18 (27): 4007–14 (ENGLAND). ISSN:0950-9232. PMID: 10435624. DOI: 10.1038/sj.onc.1202776.

[pmid12015309-49] Vieyra, Diego, Loewith Robbie, Scott Michelle, Bonnefin Paul, Boisvert Francois-Michel, Cheema Parneet, Pastyryeva Svitlana, Meijer Maria, Johnston Randal N, Bazett-Jones David P, McMahon Steven, Cole Michael D, Young Dallan, Riabowol Karl (Aug. 2002). Human ING1 proteins differentially regulate histone acetylation. J. Biol. Chem. 277 (33): 29832–9 (United States). ISSN:0021-9258. PMID: 12015309. DOI: 10.1074/jbc.M200197200.

[pmid12496368-50] Hong, Wei, Resnick Ross J, Rakowski Carrie, Shalloway David, Taylor Steven J, Blobel Gerd A (Nov. 2002). Physical and functional interaction between the transcriptional cofactor CBP and the KH domain protein Sam68. Mol. Cancer Res. 1 (1): 48–55 (United States). ISSN:1541-7786. PMID: 12496368.

[pmid11748222-51] Song, Chao-Zhong, Keller Kimberly, Murata Ken, Asano Haruhiko, Stamatoyannopoulos George (Mar. 2002). Functional interaction between coactivators CBP/p300, PCAF, and transcription factor FKLF2. J. Biol. Chem. 277 (9): 7029–36 (United States). ISSN:0021-9258. PMID: 11748222. PMC: 2808425. DOI: 10.1074/jbc.M108826200.

[pmid10666450-52] Geiman, D E, Ton-That H, Johnson J M, Yang V W (Mar. 2000). Transactivation and growth suppression by the gut-enriched Krüppel-like factor (Krüppel-like factor 4) are dependent on acidic amino acid residues and protein-protein interaction. Nucleic Acids Res. 28 (5): 1106–13 (ENGLAND). PMID: 10666450. PMC: 102607. DOI: 10.1093/nar/28.5.1106.

[pmid9488450-53] Barlev, N A, Poltoratsky V, Owen-Hughes T, Ying C, Liu L, Workman J L, Berger S L (Mar. 1998). Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex. Mol. Cell. Biol. 18 (3): 1349–58 (UNITED STATES). ISSN:0270-7306. PMID: 9488450. PMC: 108848.

[pmid11943779-54] Chen, Qin, Dowhan Dennis H, Liang Dongcai, Moore David D, Overbeek Paul A (Jul. 2002). CREB-binding protein/p300 co-activation of crystallin gene expression. J. Biol. Chem. 277 (27): 24081–9 (United States). ISSN:0021-9258. PMID: 11943779. DOI: 10.1074/jbc.M201821200.

[pmid12205094-55] Goto, Natalie K, Zor Tsaffrir, Martinez-Yamout Maria, Dyson H Jane, Wright Peter E (Nov. 2002). Cooperativity in transcription factor binding to the coactivator CREB-binding protein (CBP). The mixed lineage leukemia protein (MLL) activation domain binds to an allosteric site on the KIX domain. J. Biol. Chem. 277 (45): 43168–74 (United States). ISSN:0021-9258. PMID: 12205094. DOI: 10.1074/jbc.M207660200.

[pmid10673036-56] Pearson, K L, Hunter T, Janknecht R (Dec. 1999). Activation of Smad1-mediated transcription by p300/CBP. Biochim. Biophys. Acta 1489 (2-3): 354–64 (NETHERLANDS). ISSN:0006-3002. PMID: 10673036. DOI: 10.1016/S0167-4781(99)00166-9.

[pmid11239394-57] Sun, Y, Nadal-Vicens M, Misono S, Lin M Z, Zubiaga A, Hua X, Fan G, Greenberg M E (Feb. 2001). Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell 104 (3): 365–76 (United States). ISSN:0092-8674. PMID: 11239394. DOI: 10.1016/S0092-8674(01)00224-0.

[pmid10215616-58] Shetty, S, Takahashi T, Matsui H, Ayengar R, Raghow R (May. 1999). Transcriptional autorepression of Msx1 gene is mediated by interactions of Msx1 protein with a multi-protein transcriptional complex containing TATA-binding protein, Sp1 and cAMP-response-element-binding protein-binding protein (CBP/p300). Biochem. J. 339 (3): 751–8 (ENGLAND). ISSN:0264-6021. PMID: 10215616. PMC: 1220213. DOI: 10.1042/0264-6021:3390751.

[pmid11423988-59] Bessa, M, Saville M K, Watson R J (Jun. 2001). Inhibition of cyclin A/Cdk2 phosphorylation impairs B-Myb transactivation function without affecting interactions with DNA or the CBP coactivator. Oncogene 20 (26): 3376–86 (England). ISSN:0950-9232. PMID: 11423988. DOI: 10.1038/sj.onc.1204439.

[pmid11463815-60] Polesskaya, A, Naguibneva I, Duquet A, Bengal E, Robin P, Harel-Bellan A (Aug. 2001). Interaction between acetylated MyoD and the bromodomain of CBP and/or p300. Mol. Cell. Biol. 21 (16): 5312–20 (United States). ISSN:0270-7306. PMID: 11463815. PMC: 87255. DOI: 10.1128/MCB.21.16.5312-5320.2001.

[pmid9001254-61] Sartorelli, V, Huang J, Hamamori Y, Kedes L (Feb. 1997). Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C. Mol. Cell. Biol. 17 (2): 1010–26 (UNITED STATES). ISSN:0270-7306. PMID: 9001254. PMC: 231826.

[pmid10567404-62] Lee, S K, Anzick S L, Choi J E, Bubendorf L, Guan X Y, Jung Y K, Kallioniemi O P, Kononen J, Trent J M, Azorsa D, Jhun B H, Cheong J H, Lee Y C, Meltzer P S, Lee J W (Nov. 1999). A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo. J. Biol. Chem. 274 (48): 34283–93 (UNITED STATES). ISSN:0021-9258. PMID: 10567404. DOI: 10.1074/jbc.274.48.34283.

[pmid11158331-63] Lee, S K, Jung S Y, Kim Y S, Na S Y, Lee Y C, Lee J W (Feb. 2001). Two distinct nuclear receptor-interaction domains and CREB-binding protein-dependent transactivation function of activating signal cointegrator-2. Mol. Endocrinol. 15 (2): 241–54 (United States). ISSN:0888-8809. PMID: 11158331. DOI: 10.1210/me.15.2.241.

[pmid11514544-64] Yang, T, Davis R J, Chow C W (Oct. 2001). Requirement of two NFATc4 transactivation domains for CBP potentiation. J. Biol. Chem. 276 (43): 39569–76 (United States). ISSN:0021-9258. PMID: 11514544. DOI: 10.1074/jbc.M102961200.

[pmid11154691-65] Hung, H L, Kim A Y, Hong W, Rakowski C, Blobel G A (Apr. 2001). Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation. J. Biol. Chem. 276 (14): 10715–21 (United States). ISSN:0021-9258. PMID: 11154691. DOI: 10.1074/jbc.M007846200.

[pmid11683914-66] Katoh, Y, Itoh K, Yoshida E, Miyagishi M, Fukamizu A, Yamamoto M (Oct. 2001). Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription. Genes Cells 6 (10): 857–68 (England). ISSN:1356-9597. PMID: 11683914. DOI: 10.1046/j.1365-2443.2001.00469.x.

[pmid11971985-67] Wu, Ray-Chang, Qin Jun, Hashimoto Yoshihiro, Wong Jiemin, Xu Jianming, Tsai Sophia Y, Tsai Ming-Jer, O'Malley Bert W (May. 2002). Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol. Cell. Biol. 22 (10): 3549–61 (United States). ISSN:0270-7306. PMID: 11971985. PMC: 133790. DOI: 10.1128/MCB.22.10.3549-3561.2002.

[pmid11076796-68] Naltner, A, Wert S, Whitsett J A, Yan C (Dec. 2000). Temporal/spatial expression of nuclear receptor coactivators in the mouse lung. Am. J. Physiol. Lung Cell Mol. Physiol. 279 (6): L1066–74 (UNITED STATES). ISSN:1040-0605. PMID: 11076796.

[pmid9858599-69] Kasper, L H, Brindle P K, Schnabel C A, Pritchard C E, Cleary M L, van Deursen J M (Jan. 1999). CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity. Mol. Cell. Biol. 19 (1): 764–76 (UNITED STATES). ISSN:0270-7306. PMID: 9858599. PMC: 83933.

[pmid12426395-70] Ito, Akihiro, Kawaguchi Yoshiharu, Lai Chun-Hsiang, Kovacs Jeffrey J, Higashimoto Yuichiro, Appella Ettore, Yao Tso-Pang (Nov. 2002). MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation. EMBO J. 21 (22): 6236–45 (England). ISSN:0261-4189. PMID: 12426395. PMC: 137207. DOI: 10.1093/emboj/cdf616.

[pmid11782467-71] Livengood, Jill A, Scoggin Kirsten E S, Van Orden Karen, McBryant Steven J, Edayathumangalam Rajeswari S, Laybourn Paul J, Nyborg Jennifer K (Mar. 2002). p53 Transcriptional activity is mediated through the SRC1-interacting domain of CBP/p300. J. Biol. Chem. 277 (11): 9054–61 (United States). ISSN:0021-9258. PMID: 11782467. DOI: 10.1074/jbc.M108870200.

[pmid11864601-72] Tini, Marc, Benecke Arndt, Um Soo-Joong, Torchia Joseph, Evans Ronald M, Chambon Pierre (Feb. 2002). Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription. Mol. Cell 9 (2): 265–77 (United States). ISSN:1097-2765. PMID: 11864601. DOI: 10.1016/S1097-2765(02)00453-7.

[pmid10558993-73] Puigserver, P, Adelmant G, Wu Z, Fan M, Xu J, O'Malley B, Spiegelman B M (Nov. 1999). Activation of PPARgamma coactivator-1 through transcription factor docking. Science 286 (5443): 1368–71 (UNITED STATES). ISSN:0036-8075. PMID: 10558993. DOI: 10.1126/science.286.5443.1368.

[pmid12622724-74] Matsuzaki, Kazuhito, Minami Takeshi, Tojo Masahide, Honda Yoshiomi, Saitoh Noriko, Nagahiro Shinji, Saya Hideyuki, Nakao Mitsuyoshi (Mar. 2003). PML-nuclear bodies are involved in cellular serum response. Genes Cells 8 (3): 275–86 (England). ISSN:1356-9597. PMID: 12622724. DOI: 10.1046/j.1365-2443.2003.00632.x.

[pmid10077561-75] Doucas, V, Tini M, Egan D A, Evans R M (Mar. 1999). Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling. Proc. Natl. Acad. Sci. U.S.A. 96 (6): 2627–32 (UNITED STATES). ISSN:0027-8424. PMID: 10077561. PMC: 15819. DOI: 10.1073/pnas.96.6.2627.

[pmid10610177-76] Zhong, S, Delva L, Rachez C, Cenciarelli C, Gandini D, Zhang H, Kalantry S, Freedman L P, Pandolfi P P (Nov. 1999). A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteins. Nat. Genet. 23 (3): 287–95 (UNITED STATES). ISSN:1061-4036. PMID: 10610177. DOI: 10.1038/15463.

[pmid11897665-77] Karetsou, Zoe, Kretsovali Adroniki, Murphy Carol, Tsolas Orestes, Papamarcaki Thomais (Apr. 2002). Prothymosin alpha interacts with the CREB-binding protein and potentiates transcription. EMBO Rep. 3 (4): 361–6 (England). ISSN:1469-221X. PMID: 11897665. PMC: 1084059. DOI: 10.1093/embo-reports/kvf071.

[pmid15140884-78] Jang, Hyun Duk, Yoon Kwiyeom, Shin Young Joo, Kim Jaesang, Lee Soo Young (Jun. 2004). PIAS3 suppresses NF-kappaB-mediated transcription by interacting with the p65/RelA subunit. J. Biol. Chem. 279 (23): 24873–80 (United States). ISSN:0021-9258. PMID: 15140884. DOI: 10.1074/jbc.M313018200.

[pmid11931769-79] Zhong, Haihong, May Michael J, Jimi Eijiro, Ghosh Sankar (Mar. 2002). The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol. Cell 9 (3): 625–36 (United States). ISSN:1097-2765. PMID: 11931769. DOI: 10.1016/S1097-2765(02)00477-X.

[pmid9548485-80] Parry, G C, Mackman N (Dec. 1997). Role of cyclic AMP response element-binding protein in cyclic AMP inhibition of NF-kappaB-mediated transcription. J. Immunol. 159 (11): 5450–6 (UNITED STATES). ISSN:0022-1767. PMID: 9548485.

[pmid9096323-81] Gerritsen, M E, Williams A J, Neish A S, Moore S, Shi Y, Collins T (Apr. 1997). CREB-binding protein/p300 are transcriptional coactivators of p65. Proc. Natl. Acad. Sci. U.S.A. 94 (7): 2927–32 (UNITED STATES). ISSN:0027-8424. PMID: 9096323. PMC: 20299. DOI: 10.1073/pnas.94.7.2927.

[pmid11564891-82] Merienne, K, Pannetier S, Harel-Bellan A, Sassone-Corsi P (Oct. 2001). Mitogen-regulated RSK2-CBP interaction controls their kinase and acetylase activities. Mol. Cell. Biol. 21 (20): 7089–96 (United States). ISSN:0270-7306. PMID: 11564891. PMC: 99884. DOI: 10.1128/MCB.21.20.7089-7096.2001.

[pmid12736710-83] Hirose, Takuji, Fujii Ryouji, Nakamura Hiroshi, Aratani Satoko, Fujita Hidetoshi, Nakazawa Minako, Nakamura Kohzo, Nishioka Kusuki, Nakajima Toshihiro (Jun. 2003). Regulation of CREB-mediated transcription by association of CDK4 binding protein p34SEI-1 with CBP. Int. J. Mol. Med. 11 (6): 705–12 (Greece). ISSN:1107-3756. PMID: 12736710.

[pmid11003650-84] DiRenzo, J, Shang Y, Phelan M, Sif S, Myers M, Kingston R, Brown M (Oct. 2000). BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation. Mol. Cell. Biol. 20 (20): 7541–9 (UNITED STATES). ISSN:0270-7306. PMID: 11003650. PMC: 86306. DOI: 10.1128/MCB.20.20.7541-7549.2000.

[pmid8918891-85] Oliner, J D, Andresen J M, Hansen S K, Zhou S, Tjian R (Nov. 1996). SREBP transcriptional activity is mediated through an interaction with the CREB-binding protein. Genes Dev. 10 (22): 2903–11 (UNITED STATES). ISSN:0890-9369. PMID: 8918891. DOI: 10.1101/gad.10.22.2903.

[pmid14716005-86] Aizawa, Hiroyuki, Hu Shu-Ching, Bobb Kathryn, Balakrishnan Karthik, Ince Gulayse, Gurevich Inga, Cowan Mitra, Ghosh Anirvan (Jan. 2004). Dendrite development regulated by CREST, a calcium-regulated transcriptional activator. Science 303 (5655): 197–202 (United States). PMID: 14716005. DOI: 10.1126/science.1089845.

[pmid8986769-87] Zhang, J J, Vinkemeier U, Gu W, Chakravarti D, Horvath C M, Darnell J E (Dec. 1996). Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling. Proc. Natl. Acad. Sci. U.S.A. 93 (26): 15092–6 (UNITED STATES). ISSN:0027-8424. PMID: 8986769. PMC: 26361. DOI: 10.1073/pnas.93.26.15092.

[pmid8848048-88] Bhattacharya, S, Eckner R, Grossman S, Oldread E, Arany Z, D'Andrea A, Livingston D M (Sep. 1996). Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha. Nature 383 (6598): 344–7 (ENGLAND). ISSN:0028-0836. PMID: 8848048. DOI: 10.1038/383344a0.

[pmid11574547-89] Litterst, C M, Pfitzner E (Dec. 2001). Transcriptional activation by STAT6 requires the direct interaction with NCoA-1. J. Biol. Chem. 276 (49): 45713–21 (United States). ISSN:0021-9258. PMID: 11574547. DOI: 10.1074/jbc.M108132200.

[pmid10454341-90] McDonald, C, Reich N C (Jul. 1999). Cooperation of the transcriptional coactivators CBP and p300 with Stat6. J. Interferon Cytokine Res. 19 (7): 711–22 (UNITED STATES). ISSN:1079-9907. PMID: 10454341. DOI: 10.1089/107999099313550.

[pmid12435739-91] Bradney, Curtis, Hjelmeland Mark, Komatsu Yasuhiko, Yoshida Minoru, Yao Tso-Pang, Zhuang Yuan (Jan. 2003). Regulation of E2A activities by histone acetyltransferases in B lymphocyte development. J. Biol. Chem. 278 (4): 2370–6 (United States). ISSN:0021-9258. PMID: 12435739. DOI: 10.1074/jbc.M211464200.

[pmid11912212-92] Misra, Parimal, Qi Chao, Yu Songtao, Shah Sejal H, Cao Wen-Qing, Rao M Sambasiva, Thimmapaya Bayar, Zhu Yijun, Reddy Janardan K (May. 2002). Interaction of PIMT with transcriptional coactivators CBP, p300, and PBP differential role in transcriptional regulation. J. Biol. Chem. 277 (22): 20011–9 (United States). ISSN:0021-9258. PMID: 11912212. DOI: 10.1074/jbc.M201739200.

[pmid11349124-93] Gizard, F, Lavallée B, DeWitte F, Hum D W (Sep. 2001). A novel zinc finger protein TReP-132 interacts with CBP/p300 to regulate human CYP11A1 gene expression. J. Biol. Chem. 276 (36): 33881–92 (United States). ISSN:0021-9258. PMID: 11349124. DOI: 10.1074/jbc.M100113200.

[pmid9806899-94] Silverman, E S, Du J, Williams A J, Wadgaonkar R, Drazen J M, Collins T (Nov. 1998). cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1). Biochem. J. 336 (1): 183–9 (ENGLAND). ISSN:0264-6021. PMID: 9806899. PMC: 1219856.