Trapidil
Trapidil is a vasodilator and an antiplatelet drug.[1][2] It also acts as an antagonist of platelet-derived growth factor.[3]
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| Trade names | Rocornal, Avantrin, Travisco |
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| Routes of administration | By mouth |
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| ECHA InfoCard | 100.035.834  |
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| Formula | C10H15N5 |
| Molar mass | 205.265 g·mol−1 |
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References
- Büyükafşar K, Yazar A, Düşmez D, Oztürk H, Polat G, Levent A (October 2001). "Effect of trapidil, an antiplatelet and vasodilator agent on gentamicin-induced nephrotoxicity in rats". Pharmacological Research. 44 (4): 321–8. doi:10.1006/phrs.2001.0864. PMID 11592868.
- Liu M, Sun Q, Wang Q, Wang X, Lin P, Yang M, Yan Y (March–April 2014). "Effect of trapidil in myocardial ischemia-reperfusion injury in rabbit". Indian Journal of Pharmacology. 46 (2): 207–10. doi:10.4103/0253-7613.129320. PMC 3987192. PMID 24741195.
- Maresta A, Balducelli M, Cantini L, Casari A, Chioin R, Fabbri M, et al. (December 1994). "Trapidil (triazolopyrimidine), a platelet-derived growth factor antagonist, reduces restenosis after percutaneous transluminal coronary angioplasty. Results of the randomized, double-blind STARC study. Studio Trapidil versus Aspirin nella Restenosi Coronarica". Circulation. 90 (6): 2710–5. doi:10.1161/01.cir.90.6.2710. PMID 7994812.
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