TECTB

TECTB
Identifiers
Aliases	TECTB, tectorin beta
External IDs	OMIM: 602653 MGI: 109574 HomoloGene: 7568 GeneCards: TECTB
Gene location (Human)
Chr.	Chromosome 10 (human)[1]
End	112,305,038 bp[1]
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)[2]
End	55,196,313 bp[2]
Gene ontology
Molecular function	• extracellular matrix structural constituent;
Cellular component	• anchored component of membrane; • membrane; • extracellular region; • cell membrane; • extracellular matrix;
Biological process	• C-terminal protein lipidation;
	Sources:Amigo / QuickGO
Orthologs
	6975
	21684
	ENSG00000119913
	ENSMUSG00000024979
	Q96PL2
	O08524
	NM_058222
	NM_009348
	NP_478129
	NP_033374
	Wikidata
View/Edit Human	View/Edit Mouse

Beta-tectorin is a protein that in humans is encoded by the TECTB gene.[5]

Function

The genes for alpha-tectorin and beta-tectorin (this protein) encode the major noncollagenous proteins of the tectorial membrane of the cochlea.[5]

GRCh38: Ensembl release 89: ENSG00000119913 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000024979 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: tectorin beta".

Legan PK, Rau A, Keen JN, Richardson GP (1997). "The mouse tectorins. Modular matrix proteins of the inner ear homologous to components of the sperm-egg adhesion system". J. Biol. Chem. 272 (13): 8791–801. doi:10.1074/jbc.272.13.8791. PMID 9079715.
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
Rose JE, Behm FM, Drgon T, et al. "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Grupe A, Li Y, Rowland C, et al. (2006). "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease". Am. J. Hum. Genet. 78 (1): 78–88. doi:10.1086/498851. PMC 1380225. PMID 16385451.

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