OR8A1

Olfactory receptor 8A1 is a protein that in humans is encoded by the OR8A1 gene.[5]

OR8A1
Identifiers
Aliases	OR8A1, OR11-318, OST025, olfactory receptor family 8 subfamily A member 1
External IDs	MGI: 1931271 HomoloGene: 12726 GeneCards: OR8A1
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q24.2 Start 124,566,660 bp[1] End 124,582,942 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A4 Start 37,708,964 bp[2] End 37,716,250 bp[2]
Gene ontology Molecular function • G-protein coupled receptor activity • signal transducer activity • olfactory receptor activity • odorant binding Cellular component • integral component of membrane • cell membrane • membrane Biological process • response to stimulus • signal transduction • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway • axon guidance Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	390275	80706
Ensembl	ENSG00000196119	ENSMUSG00000061165
UniProt	Q8NGG7	Q8VGE3
RefSeq (mRNA)	NM_001005194	NM_030553
RefSeq (protein)	NP_001005194	NP_085030
Location (UCSC)	Chr 11: 124.57 – 124.58 Mb	Chr 9: 37.71 – 37.72 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]