OR2A1

Olfactory receptor 2A1/2A42 is a protein that in humans is encoded by the OR2A1 gene.[4]

OR2A1
Identifiers
Aliases	OR2A1, olfactory receptor family 2 subfamily A member 1
External IDs	MGI: 3030269 HomoloGene: 110586 GeneCards: OR2A1
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q35 Start 144,312,464 bp[1] End 144,322,668 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	346528	258647
Ensembl	ENSG00000221970 ENSG00000285105	n/a
UniProt	Q8NGT9	Q8VFS3
RefSeq (mRNA)	NM_001005287	NM_146653
RefSeq (protein)	NP_001005287	NP_666864
Location (UCSC)	Chr 7: 144.31 – 144.32 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]