Dihydropicrotoxinin

Dihydropicrotoxinin
Identifiers
CAS Number	17617-46-8;
3D model (JSmol)	Interactive image;
ChemSpider	108864;
PubChem CID	122052;
	InChI InChI=1S/C15H18O6/c1-5(2)7-8-11(16)19-9(7)10-13(3)14(8,18)4-6-15(13,21-6)12(17)20-10/h5-10,18H,4H2,1-3H3/t6?,7?,8-,9?,10-,13-,14-,15?/m1/s1 Key: SJSFJVFGSPJGET-KJINDDCRSA-N;
	SMILES CC(C)C1[C@@H]2C(=O)OC1[C@@H]3[C@@]4([C@]2(CC5C4(O5)C(=O)O3)O)C;
Properties
Chemical formula	C15H18O6
Molar mass	294.303 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Dihydropicrotoxinin is the saturated derivative of picrotoxinin. Its radiolabeled derivative, [³H]dihydropicrotoxinin, is used in scientific research to study the GABA receptors.[1]

References

Olsen, R. W (2006). "Picrotoxin-like channel blockers of GABAA receptors". Proceedings of the National Academy of Sciences of the United States of America. 103 (16): 6081–2. doi:10.1073/pnas.0601121103. PMC 1458832. PMID 16606858.

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[1] Olsen, R. W (2006). "Picrotoxin-like channel blockers of GABAA receptors". Proceedings of the National Academy of Sciences of the United States of America. 103 (16): 6081–2. doi:10.1073/pnas.0601121103. PMC 1458832. PMID 16606858.

Convulsants
GABA receptor antagonists	Picrotoxin Gabazine Tetramethylenedisulfotetramine Cicutoxin Phenylsilatrane Tutin Pentylenetetrazol Thujone Endosulfan Bicuculline Oenanthotoxin Fipronil EBOB BIDN Dihydropicrotoxinin DMCM FG-7142 Chlorophenylsilatrane Bicyclic phosphates (TBPS, TBPO, IPTBO) Flurothyl
GABA synthesis inhibitors	Allylglycine Crimidine Ginkgotoxin Toxopyrimidine Isoniazid 3-Mercaptopropionic acid 4-Deoxypyridoxine
Glycine receptor antagonists	Strychnine Tutin Picrotoxin Dendrobine
Glutamate receptor agonists	AMPA NMDA Kainic acid Domoic acid Quisqualic acid Tetrazolylglycine
Other	Methyl fluoroacetate Fluoroethyl fluoroacetate Nitrocyclohexane Methionine sulfoximine

Dihydropicrotoxinin

See also

References