Clofibride

Clofibride is a fibrate. Clofibride is a derivative of clofibrate. In the body it is converted into 4-chlorophenoxyisobutyric acid (clofibric acid)[1], which is the true hypolipidemic agent[2]. So clofibride, just like clofibrate is a prodrug of clofibric acid.

Clofibride
Clinical data
ATC code
Pharmacokinetic data
MetabolismHydrolyzed to clofibric acid; hepatic glucuronidation
Elimination half-life12 hours (clofibric acid)
ExcretionRenal (mostly) and fecal
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.043.542
Chemical and physical data
FormulaC16H22ClNO4
Molar mass327.81 g·mol−1
3D model (JSmol)
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References

  1. https://pubchem.ncbi.nlm.nih.gov/compound/160134
  2. Entry on Clofibrat. at: Römpp Online. Georg Thieme Verlag, retrieved 06. Mai 2020.


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