Vomifoliol dehydrogenase

vomifoliol 4'-dehydrogenase
Identifiers
EC number 1.1.1.221
CAS number 94949-18-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a vomifoliol dehydrogenase (EC 1.1.1.221) is an enzyme that catalyzes the chemical reaction

(6S,9R)-6-hydroxy-3-oxo-alpha-ionol + NAD+ (6R)-6-hydroxy-3-oxo-alpha-ionone + NADH + H+

Thus, the two substrates of this enzyme are (6S,9R)-6-hydroxy-3-oxo-alpha-ionol and NAD+, whereas its 3 products are (6R)-6-hydroxy-3-oxo-alpha-ionone, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is vomifoliol:NAD+ oxidoreductase. Other names in common use include vomifoliol 4'-dehydrogenase, and vomifoliol:NAD+ 4'-oxidoreductase.

References

    • Hasegawa S, Poling SM, Maier VP, Bennett RD (1984). "Metabolism of abscisic-acid bacterial conversion to dehydrovomifoliol and vomifoliol dehydrogenase-activity". Phytochemistry. 23 (12): 2769&ndash, 2771. doi:10.1016/0031-9422(84)83012-5.
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