UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase

UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase
Identifiers
EC number 2.4.2.42
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase (EC 2.4.2.42, beta-glucoside alpha-1,3-xylosyltransferase) is an enzyme with systematic name UDP-alpha-D-xylose:beta-D-glucoside 3-alpha-D-xylosyltransferase.[1][2] This enzyme catalyses the following chemical reaction

UDP-alpha-D-xylose + Glcbeta-Ser53-EGF-like domain of bovine factor IX(45-87) UDP + Xylalpha(1-3)Glcbeta-Ser53-EGF-like domain of bovine factor IX(45-87)

The enzyme is involved in the biosynthesis of the Xylalpha(1-3)Xylalpha(1-3)Glcbeta-1-O-Ser on epidermal growth factor-like domains.

References

  1. ↑ Ishimizu, T.; Sano, K.; Uchida, T.; Teshima, H.; Omichi, K.; Hojo, H.; Nakahara, Y.; Hase, S. (2007). "Purification and substrate specificity of UDP-D-xylose:β-D-glucoside α-1,3-D-xylosyltransferase involved in the biosynthesis of the Xyl α1-3Xyl α1-3Glc β1-O-Ser on epidermal growth factor-like domains". J. Biochem. 141: 593–600. doi:10.1093/jb/mvm064. PMID 17317689.
  2. ↑ Omichi, K.; Aoki, K.; Minamida, S.; Hase, S. (1997). "Presence of UDP-D-xylose: β-D-glucoside α-1,3-D-xylosyltransferase involved in the biosynthesis of the Xyl α 1-3Glc β-Ser structure of glycoproteins in the human hepatoma cell line HepG2". Eur. J. Biochem. 245: 143–146. doi:10.1111/j.1432-1033.1997.00143.x. PMID 9128735.
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