Trimethylsulfonium—tetrahydrofolate N-methyltransferase
trimethylsulfonium-tetrahydrofolate N-methyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.1.1.19 | ||||||||
CAS number | 37256-92-1 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a trimethylsulfonium-tetrahydrofolate N-methyltransferase (EC 2.1.1.19) is an enzyme that catalyzes the chemical reaction
- trimethylsulfonium + tetrahydrofolate dimethylsulfide + 5-methyltetrahydrofolate
Thus, the two substrates of this enzyme are trimethylsulfonium and tetrahydrofolate, whereas its two products are dimethyl sulfide and 5-methyltetrahydrofolate.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is trimethylsulfonium:tetrahydrofolate N-methyltransferase. This enzyme is also called trimethylsulfonium-tetrahydrofolate methyltransferase. This enzyme participates in one carbon pool by folate.
References
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