Tetrahydrosarcinapterin synthase

Tetrahydrosarcinapterin synthase
Identifiers
EC number 6.3.2.33
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Tetrahydrosarcinapterin synthase (EC 6.3.2.33, H4MPT:alpha-L-glutamate ligase, MJ0620, MptN protein) is an enzyme with systematic name tetrahydromethanopterin:alpha-L-glutamate ligase (ADP-forming).[1] This enzyme catalyses the following chemical reaction

ATP + tetrahydromethanopterin + L-glutamate ADP + phosphate + 5,6,7,8-tetrahydrosarcinapterin

This enzyme catalyses the biosynthesis of 5,6,7,8-tetrahydrosarcinapterin.

References

  1. Li, H.; Xu, H.; Graham, D.E.; White, R.H. (2003). "Glutathione synthetase homologs encode α-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses". Proc. Natl. Acad. Sci. USA. 100: 9785–9790. doi:10.1073/pnas.1733391100. PMC 187843. PMID 12909715.
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