Sedoheptulose

Sedoheptulose
Names
IUPAC name
(3S,4R,5R,6R)-1,3,4,5,6,7-Hexahydroxyheptan-2-one
Other names
D-altro-2-Heptulose; D-altro-Heptulose
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.019.243
MeSH Sedoheptulose
Properties
C7H14O7
Molar mass 210.18 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Sedoheptulose or D-altro-heptulose is a ketoheptose—a monosaccharide with seven carbon atoms and a ketone functional group. It is one of the few heptoses found in nature. Sedoheptulose is found in various fruits and vegetables ranging from carrots, apricots, apples to tomatoes.[1]

It is an intermediate in respiratory and photosynthetic pathways and plays a vital role in the non-oxidative branch of the pentose phosphate pathway.[2][3]

Studies have shown that sedoheptulose is able to reduce pro-inflammatory markers in vitro such as interleukin-6 (IL-6) and C-reactive protein and thus might be able reduce low-level inflammation in humans.

See also

References

  1. ↑ Kardon, Tamas; Stroobant, Vincent; Veiga-Da-Cunha, Maria; Schaftingen, Emile Van (2008). "Characterization of mammalian sedoheptulokinase and mechanism of formation of erythritol in sedoheptulokinase deficiency". FEBS Letters. 582 (23–24): 3330. doi:10.1016/j.febslet.2008.08.024. PMID 18775706.
  2. ↑ Horecker, B. L; Smyrniotis, P. Z (1953). "Transaldolase: The Formation of Fructose-6-Phosphate from Sedoheptulose-7-Phosphate". Journal of the American Chemical Society. 75 (8): 2021. doi:10.1021/ja01104a532.
  3. ↑ Patra, Krushna C; Hay, Nissim (2014). "The pentose phosphate pathway and cancer". Trends in Biochemical Sciences. 39 (8): 347. doi:10.1016/j.tibs.2014.06.005. PMC 4329227. PMID 25037503.
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