Sean P. F. Hughes

Professor
Sean P. F. Hughes
MA(Hist), MS, FRCSEd(Orth), FRCS, FRCSI[1] DHMSA [2], DPMSA
Sean P. F. Hughes 2018, at the Worshipful Society of Apothecaries
Born Sean Patrick Francis Hughes
December 1941
Education
Known for
Medical career
Profession Orthopedic Surgery
Institutions
Research

Sean Patrick Francis Hughes (b. December 1941)[3] is Emeritus Professor of orthopaedic surgery at Imperial College London where he was previously Professor of Orthopaedic Surgery and head of the department of surgery, anaesthetics and intensive care. Earlier in his career he had been Professor of Orthopaedic Surgery at the University of Edinburgh.[4]

His clinical research interests have included fracture healing, musculoskeletal infection and the surgery of degenerate  lumbar and cervical discs. His basic science research publications include studies of the microcirculation of bone, bone infection and the role of nitric oxide in bone and joint disease.[5] He served as Vice President of the Royal College of Surgeons of Edinburgh[1] and chairman of DISCS, the charity funding research into spinal conditions.[6]

His interests in the history of medicine have focused on the history of orthopaedic surgery[2] and the doctor and poet John Keats.[7]

Early life and training

Hughes was born in Farnham, Surrey, England[3] and attended school at Downside School. He studied medicine at the University of London, qualifying with an MB BS in 1966.[8] His surgical training in orthopaedics took place in London and he became a senior registrar in orthopaedic and trauma surgery at the Middlesex Hospital and the Royal National Orthopaedic Hospital. He attained his FRCSEd in 1971 and FRCSEng and FRCSI the following year. Subsequently he was awarded the degree of MS from University of London with a thesis on bone scanning, completed while he was research fellow at the Mayo Clinic, Rochester, Minnesota.[9]

Surgical career

In 1979 he was appointed Senior Lecturer and Honorary Consultant Orthopaedic Surgeon, Royal Postgraduate Medical School in London. Later that year he was appointed to the Chair of Orthopaedic Surgery at the University of Edinburgh. In 1984/85 he held an academic mentorship for Rüdiger Döhler.

He was listed as a member, in the International Skeletal Society's 25th anniversary book.[10]

In 1991 he became Professor of Orthopaedic Surgery, Imperial College London and Honorary Consultant Orthopaedic Surgeon, Hammersmith Hospitals NHS Trust (1991–2006). At the same time he took on the role of Chief of Service Orthopaedics and Trauma Surgery, Hammersmith Hospitals NHS Trust, a post which he held until 1998, when he became the Trust's Clinical Director for Surgery and Anaesthetics. He was Non-Executive Director of the West Middlesex University Hospital (2001-2005) and was Medical Director of Ravenscourt Park Hospital from 2002-2004. Hughes was Clinical Director of the Hillingdon Primary Care Trust from 2008-10.

In addition to his clinical and academic responsibilities, he was Vice President of the Royal College of Surgeons of Edinburgh (1994-97) and President of the British Orthopaedic Research Society (1995-97). He served as chairman of the charity Action Research, now called Action Medical Research (1998-1991).[11]

He was on the International Advisory Board of the Journal of Orthopaedics, Trauma.[12] and was Chairman of the charity Discovering Innovative Solutions for Conditions of the Spine (DISCS).[6]

Currently (2018) he is a primary editor of the Bone and Joint Journal.[13]

Hughes performed basic research on bone blood flow mineral exchange, musculoskeletal infections and stem cell research. He has a special interest in degenerative disc disease and external fixation of fractures (Hughes-Suhktian fixator).[14]

History of Medicine

Hughes has lectured on the history of orthopaedics.[2] In addition, he gave the eponymous Keats lecture at the Worshipful Society of Apothecaries in 2017[7]

Personal life

He is married to Felicity Hughes (née Anderson), a retired medical microbiologist.[10]

Academic distinctions

  • Arris and Gale Lecturer, Royal College of Surgeons, 1976.[15]
  • Seddon Prize, Royal National Orthopaedic Hospital, 1976.[15]
  • U.K. Travelling Fellow, British Orthopaedic Association, 1977
  • A.B.C. Travelling Fellow, British Orthopaedic Association, 1978
  • Scandinavian Travelling Fellow, British and Scandinavian Orthopaedic Association, 1986
  • Visiting Clinical Scientist, Mayo Clinic, Rochester, USA, 1989
  • Rahima Dawood Travelling Professor, East African Associations of Surgeons, 1992
  • Patrick Kelly Visiting Professor, Mayo Clinic, USA, 2000
  • Walter Mercer Lecturer, British Orthopaedic Association, 2004
  • President’s Medal from the British Orthopaedic Research Society, September 2017.[7]

Selected publications

Hughes wrote or contributed to 216 total publications in scientific journals, thirty-two chapters in books and thirteen books.[5]

Papers

  • "The distribution of 99mTc-EHDP in the tissues of the dog and its application in the assessment of fracture healing", Annals of the Royal College of Surgeons of England (I977) vol 59, pp.322-327
  • "Experience with the Sukhtian--Hughes external fixation system", co-authored with C. Court-Brown, J R Soc Med. December 1982, PMID 6757433 pp.949-57.
  • Fibrous dysplasia of bone and the Weil-Albright syndrome, with J.R. Döhler, International Orthopaedics, 10 (1986), 53-62.
  • The Cervical Disc, in : Bailliere's Clinical Orthopaedics - International Practice and Research; Vol. 2, Number 2, August 1997.
  • Nitric Oxide in Bone and Joint, with Mika V. J. Hukkanen, Julia M. Polak, Postgraduate Medical Science, 2010.
  • "Person or system – What leads to surgical advances?", co-authored with DAVID R. DAVIES, JAMES B. BASSINGTHWAIGHTE, FRANKLYN G. KNOX, and PATRICK J. KELLY, Journal of Medical Biography, 3 October 2017, doi:10.1177/0967772017732440.
  • Bone extraction and blood clearance of diphosphonate in the dog, American Journal of Physiology, 1977.

Books

  • Bone Circulation and Vascularization in Normal and Pathological Conditions, with A. Schoutens, J. Arlet, J.W.M. Gardeniers, (NATO Science Series: A), 31 July 1993
  • Textbook of Orthopaedics & Fractures, co-authored with Richard W. Porter, Taylor & Francis (1997), ISBN 978-0-340-61381-8.

Book chapters

  • "Fibröse Knochendysplasie und Weil-Albright-Syndrom", co-authored with J.R. Döhler in Walter Blauth and Hans-Wolfram Ulrich's Spätergebnisse in der Orthopädie, Springer-Verlag (1986), ISBN 9783642710292.
  • “The Regulation of Blood Flow in Bone”, co-authored with Corbett SA, Reichert ILH, McCarthy ID, Osteonecrosis (Urbaniak JR, Jones JP), American Academy of Orthopaedic Surgeons, 1997, Urbaniak JR, Jones JP, ch2, 11-19.
  • "The Use of Mesenchymal Stem Cells for Bone and Cartilage Repair", co-authored with R. Behan, N. A. Habib, M. Y. Gordon and N. Levičar, Stem Cell Repair And Regeneration, 2008, Imperial College Press, ISBN 978-1-86094-980-7.

Book reviews

References

  1. 1 2 Natasa Levicar (2008). Stem Cell Repair and Regeneration. 3. Imperial College Press. p. 13. ISBN 1-86094-980-0.
  2. 1 2 3 "2015 Meeting Blogs". West Sussex History of Medicine Society. 5 November 2015. Retrieved 18 September 2018.
  3. 1 2 "England and Wales Birth Registration Index. Sean P F Hughes". Family Search. 1941. Retrieved 15 September 2018. (subscription required)
  4. ↑ DHMSA, Sean Patrick HughesImperial College London | Imperial · Division of Surgery 41 71 · MS FRCSEd(Orth; FRCS; FRCSI;. "Sean Patrick Hughes | MS FRCSEd(Orth; FRCS; FRCSI; DHMSA | Imperial College London, London | Imperial | Division of Surgery". ResearchGate. Retrieved 19 September 2018.
  5. 1 2 ResearchGate. "Sean Patrick Hughes | MS FRCSEd(Orth; FRCS; FRCSI; DHMSA | Imperial College London, London | Imperial | Division of Surgery". ResearchGate. Retrieved 2018-10-03.
  6. 1 2 "Discovering Innovative Solutions for Conditions of the Spine | DISCs". www.discsfoundation.org. Retrieved 2018-09-18.
  7. 1 2 3 "Just how did John Keats's medical training influence his poetry? - Surgery and Cancer Blog". Surgery and Cancer Blog. 4 October 2017. Retrieved 14 September 2018.
  8. ↑ "Linkedin- Sean P. F. Hughes". Retrieved 19 September 2018.
  9. ↑ Hughes, Sean P. F. (1977). "The distribution of 99mTc-EHDP in the tissues of the dog and its application in the assessment of fracture healing". Annals of the Royal College of Surgeons of England. 59.
  10. 1 2 Kricun, Morrie E. (2012). International Skeletal Society Membership Book. Philadelphia: Springer Science & Business Media. p. 138. ISBN 978-3-642-72122-9.
  11. ↑ "Action Medical Research | Children's Charity". www.action.org.uk. Retrieved 2018-10-02.
  12. ↑ Journal of Orthopaedics, Trauma and Rehabilitation Editorial Board.
  13. ↑ Editorial Board. "The Bone and Joint Journal". online.boneandjoint.org.uk. Retrieved 4 October 2018.
  14. ↑ Leung, P.C. (2012). "2. Biomechanics of Fracture Repair and Fracture Fixation". Current Practice of Fracture Treatment: New Concepts and Common Problems. Springer-Verlag. p. 42. ISBN 978-3-642-78605-1.
  15. 1 2 Heuck, Friedrich H.W. (6 December 2012). International Skeletal Society Book of Members. Springer Verlag. p. 118. ISBN 978-3-642-97056-6.
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