S100G

S100G
Identifiers
AliasesS100G, CABP, CABP1, CABP9K, CALB3, S100 calcium binding protein G
External IDsMGI: 104528 HomoloGene: 36150 GeneCards: S100G
Gene location (Human)
Chr.X chromosome (human)[1]
BandXp22.2Start16,650,158 bp[1]
End16,654,670 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

795

12309

Ensembl

ENSG00000169906

ENSMUSG00000040808

UniProt

P29377

P97816

RefSeq (mRNA)

NM_004057

NM_009789

RefSeq (protein)

NP_004048

NP_033919

Location (UCSC)Chr X: 16.65 – 16.65 MbChr X: 162.96 – 162.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

S100 calcium-binding protein G (S100G) is a protein that in humans is encoded by the S100G gene.[5][6][7]

This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium-binding proteins that includes calmodulin, parvalbumin, troponin C, and S100 protein. In the intestine, the protein is vitamin D-dependent and its expression correlates with calcium transport activity. The protein may increase Ca2+ absorption by buffering Ca2+ in the cytoplasm and increase ATP-dependent Ca2+ transport in duodenal basolateral membrane vesicles.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000169906 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000040808 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Howard A, Legon S, Spurr NK, Walters JR (1992). "Molecular cloning and chromosomal assignment of human calbindin-D9k". Biochem Biophys Res Commun. 185 (2): 663–9. doi:10.1016/0006-291X(92)91676-H. PMID 1610358.
  6. ↑ Jeung EB, Krisinger J, Dann JL, Leung PC (Sep 1992). "Molecular cloning of the full-length cDNA encoding the human calbindin-D9k". FEBS Lett. 307 (2): 224–8. doi:10.1016/0014-5793(92)80772-9. PMID 1379540.
  7. 1 2 "Entrez Gene: S100G S100 calcium binding protein G".

Further reading

  • Balmain N (1991). "Calbindin-D9k. A vitamin-D-dependent, calcium-binding protein in mineralized tissues". Clin. Orthop. Relat. Res. (265): 265–76. PMID 2009668.
  • Fleet JC, Hock JM (1995). "Identification of osteocalcin mRNA in nonosteoid tissue of rats and humans by reverse transcription-polymerase chain reaction". J. Bone Miner. Res. 9 (10): 1565–73. doi:10.1002/jbmr.5650091009. PMID 7817802.
  • Jeung EB, Leung PC, Krisinger J (1994). "The human calbindin-D9k gene. Complete structure and implications on steroid hormone regulation". J. Mol. Biol. 235 (4): 1231–8. doi:10.1006/jmbi.1994.1076. PMID 8308886.
  • Barley NF, Prathalingam SR, Zhi P, et al. (1999). "Factors involved in the duodenal expression of the human calbindin-D9k gene". Biochem. J. 341 (3): 491–500. doi:10.1042/0264-6021:3410491. PMC 1220384. PMID 10417310.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Wang L, Klopot A, Freund JN, et al. (2004). "Control of differentiation-induced calbindin-D9k gene expression in Caco-2 cells by cdx-2 and HNF-1α". Am. J. Physiol. Gastrointest. Liver Physiol. 287 (5): G943–53. doi:10.1152/ajpgi.00121.2004. PMC 2701355. PMID 15217781.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
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