Pregnanetriol

Pregnanetriol
Names
IUPAC name
(3R,5R,8R,9S,10S,13S,14S,17R)-17-[(1S)-1-hydroxyethyl]-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol
Other names
5β-Pregnane-3α,17α,20α-triol
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.012.862
UNII
Properties
C21H36O3
Molar mass 336.52 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Pregnanetriol, or 5β-pregnane-3α,17α,20α-triol, is a steroid and inactive metabolite of progesterone.

Urine testing

Urine excretion of pregnanetriol can be measured over a period of 24 hours. Elevated urine pregnanetriol levels suggest adrenogenital syndrome. In monitoring treatment with cortisol replacement, elevated urine pregnanetriol levels indicate insufficient dosage of cortisol.[1]

Reference ranges

For females:[1]

  • 0 to 5 years: < 0.1 mg/24 hours
  • 6 to 9 years: < 0.3 mg/24 hours
  • 10 to 15 years: 0.1 to 0.6 mg/24 hours
  • 16 years and older: 0 to 1.4 mg/ 24 hours.

For males:[1]

  • 0 to 5 years: < 0.1 mg/24 hours
  • 6 to 9 years: < 0.3 mg/24 hours
  • 10 to 15 years: 0.2 to 0.6 mg/24 hours
  • 16 years and older: 0.2 to 2 mg/ 24 hours

References

  1. 1 2 3 online-family-doctor.com Pregnanetriol Retrieved April 2011


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