Pirlimycin

Pirlimycin
Clinical data
Routes of; administration	Intramammary
ATCvet code	QJ51FF90 (WHO) ;
Identifiers
	IUPAC name Methyl (2S-cis)-7-chloro-6,7,8-trideoxy-6[[(4-ethyl-2-piperidinyl)carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside;
CAS Number	79548-73-5 ;
ChemSpider	138508 ;
UNII	LM19JT6G5K;
KEGG	D08391 ;
ChEMBL	CHEMBL1652611 ;
Chemical and physical data
Formula	C17H31ClN2O5S
Molar mass	410.164 g/mol
3D model (JSmol)	Interactive image;
	SMILES CC[C@@H]1CCN[C@@H](C1)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@H](C)Cl;
	InChI InChI=1S/C17H31ClN2O5S/c1-4-9-5-6-19-10(7-9)16(24)20-11(8(2)18)15-13(22)12(21)14(23)17(25-15)26-3/h8-15,17,19,21-23H,4-7H2,1-3H3,(H,20,24)/t8-,9+,10-,11+,12-,13+,14+,15+,17+/m0/s1 ; Key:HBJOXQRURQPDEX-MHXMMLMNSA-N ;
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Pirlimycin hydrochloride belongs to the lincosamide class of antimicrobials. Under the trade name Pirsue,^[1] it is used in the treatment of mastitis in cattle.

Activity

It is bacteriostatic and acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome.

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Clinical data


Routes of administration	Intramammary
ATCvet code	QJ51FF90 (WHO)
Identifiers
IUPAC name Methyl (2S-cis)-7-chloro-6,7,8-trideoxy-6[[(4-ethyl-2-piperidinyl)carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside
CAS Number	79548-73-5^Y
ChemSpider	138508^N
UNII	LM19JT6G5K
KEGG	D08391^Y
ChEMBL	CHEMBL1652611^N
Chemical and physical data
Formula	C₁₇H₃₁ClN₂O₅S
Molar mass	410.164 g/mol
3D model (JSmol)	Interactive image
SMILES CC[C@@H]1CCN[C@@H](C1)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@H](C)Cl
InChI InChI=1S/C17H31ClN2O5S/c1-4-9-5-6-19-10(7-9)16(24)20-11(8(2)18)15-13(22)12(21)14(23)17(25-15)26-3/h8-15,17,19,21-23H,4-7H2,1-3H3,(H,20,24)/t8-,9+,10-,11+,12-,13+,14+,15+,17+/m0/s1^N Key:HBJOXQRURQPDEX-MHXMMLMNSA-N^N
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