Phytoene desaturase (neurosporene-forming)
| Phytoene desaturase (neurosporene-forming) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.3.99.28 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Phytoene desaturase (neurosporene-forming) (EC 1.3.99.28, 3-step phytoene desaturase, three-step phytoene desaturase, phytoene desaturase (ambiguous), CrtI (ambiguous)) is an enzyme with systematic name 15-cis-phytoene:acceptor oxidoreductase (neurosporene-forming).[1][2] This enzyme catalyses the following chemical reaction
- 15-cis-phytoene + 3 acceptor all-trans-neurosporene + 3 reduced acceptor (overall reaction)
- (1a) 15-cis-phytoene + acceptor all-trans-phytofluene + reduced acceptor
- (1b) all-trans-phytofluene + acceptor all-trans-zeta-carotene + reduced acceptor
- (1c) all-trans-zeta-carotene + acceptor all-trans-neurosporene + reduced acceptor
This enzyme is involved in carotenoid biosynthesis.
References
- ↑ Raisig, A.; Bartley, G.; Scolnik, P.; Sandmann, G. (1996). "Purification in an active state and properties of the 3-step phytoene desaturase from Rhodobacter capsulatus overexpressed in Escherichia coli". J. Biochem. 119 (3): 559–564. doi:10.1093/oxfordjournals.jbchem.a021278. PMID 8830054.
- ↑ Wang, C.W.; Liao, J.C. (2001). "Alteration of product specificity of Rhodobacter sphaeroides phytoene desaturase by directed evolution". J. Biol. Chem. 276 (44): 41161–41164. doi:10.1074/jbc.M105786200. PMID 11526111.
External links
- Phytoene+desaturase+(neurosporene-forming) at the US National Library of Medicine Medical Subject Headings (MeSH)
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