PABPC3

PABPC3
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesPABPC3, PABP3, PABPL3, tPABP, poly(A) binding protein cytoplasmic 3
External IDsHomoloGene: 118007 GeneCards: PABPC3
Gene location (Human)
Chr.Chromosome 13 (human)[1]
Band13q12.13Start25,095,868 bp[1]
End25,099,254 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

5042

n/a

Ensembl

ENSG00000151846

n/a

UniProt

Q9H361

n/a

RefSeq (mRNA)

NM_030979

n/a

RefSeq (protein)

NP_112241

n/a

Location (UCSC)Chr 13: 25.1 – 25.1 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Polyadenylate-binding protein 3 is a protein that in humans is encoded by the PABPC3 gene.[3][4][5]

Messenger RNA stability and translation initiation are extensively under the control of poly(A)-binding proteins] (PABP). See PABPC1 (MIM 604679) for background information.[supplied by OMIM][5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000151846 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:".
  3. ↑ Morris CM, Bodger MP (Mar 1993). "Localization of the human poly(A)-binding protein gene (PAB1) to chromosomal regions 3q22-q25, 12q13-q14, and 13q12-q13 by in situ hybridization". Genomics. 15 (1): 209–11. doi:10.1006/geno.1993.1037. PMID 8432538.
  4. ↑ Feral C, Mattei MG, Pawlak A, Guellaen G (Nov 1999). "Chromosomal localization of three human poly(A)-binding protein genes and four related pseudogenes". Hum Genet. 105 (4): 347–53. doi:10.1007/s004390051113. PMC 1865476. PMID 10543404.
  5. 1 2 "Entrez Gene: PABPC3 poly(A) binding protein, cytoplasmic 3".

Further reading

  • Marques AC, Dupanloup I, Vinckenbosch N, et al. (2006). "Emergence of young human genes after a burst of retroposition in primates". PLoS Biol. 3 (11): e357. doi:10.1371/journal.pbio.0030357. PMC 1251493. PMID 16201836.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Féral C, Guellaën G, Pawlak A (2002). "Human testis expresses a specific poly(A)-binding protein". Nucleic Acids Res. 29 (9): 1872–83. doi:10.1093/nar/29.9.1872. PMC 37253. PMID 11328870.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Hoshino S, Imai M, Kobayashi T, et al. (1999). "The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein". J. Biol. Chem. 274 (24): 16677–80. doi:10.1074/jbc.274.24.16677. PMID 10358005.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.