List of growth hormone secretagogues
This is a list of growth hormone secretagogues (GSH), or drugs that induce the secretion of growth hormone (GH).
GHRH receptor agonists
Peptide
- CJC-1295 (DAC:GRF)
- Dumorelin
- GHRH (somatocrinin, GRF, GHRF)
- Modified GRF (1-29)
- Rismorelin
- Sermorelin (Geref, Gerel; GHRH (1-29))
- Somatorelin
- Tesamorelin (Egrifta)
Ghrelin (GHS) receptor agonists
Peptide
- Alexamorelin
- Examorelin (hexarelin; EP-23905, MF-6003)
- Ghrelin (GHRL)
- GHRP-1
- GHRP-3
- GHRP-4
- GHRP-5
- GHRP-6 (SKF-110679)
- Ipamorelin (NNC 26-0161)
- Lenomorelin
- Pralmorelin (GHRP-2) (GHRP Kaken 100; GHRP-2; KP-102, GPA-748, WAY-GPA-748)
- Relamorelin (RM-131, BIM-28131, BIM-28163)
- Tabimorelin (NN-703)
Non-peptide
- Adenosine
- Anamorelin (ONO-7643, RC-1291, ST-1291)
- Capromorelin (CP-424391)
- Ibutamoren (MK-677, MK-0677, L-163191)
- Macimorelin (AEZS-130, JMV 1843)
- SM-130686
Note that while ulimorelin is a ghrelin receptor agonist, it is not a GHS as it is peripherally selective and has little or no effect on GH secretion.[1]
References
- ↑ Fraser GL, Hoveyda HR, Tannenbaum GS (2008). "Pharmacological demarcation of the growth hormone, gut motility and feeding effects of ghrelin using a novel ghrelin receptor agonist". Endocrinology. 149 (12): 6280–8. doi:10.1210/en.2008-0804. PMID 18719021.
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