| Country |
City |
IATA |
ICAO |
Airport |
Notes/Refs |
| Argentina | Buenos Aires | EZE | SAEZ | Ministro Pistarini International Airport | |
| Argentina | Córdoba | COR | SACO | Ingeniero Ambrosio L.V. Taravella International Airport | |
| Argentina | Mendoza | MDZ | SAME | Governor Francisco Gabrielli International Airport | |
| Argentina | Rosario | ROS | SAAR | Rosario – Islas Malvinas International Airport | |
| Argentina | Salta | SLA | SASA | Martín Miguel de Güemes International Airport | |
| Argentina | San Miguel de Tucumán | TUC | SANT | Teniente General Benjamín Matienzo International Airport | |
| Bolivia | Bolivia | LPB | SLLP | El Alto International Airport | |
| Bolivia | Santa Cruz de la Sierra | VVI | SLVR | Viru Viru International Airport | |
| Brazil | Foz do Iguaçu | IGU | SBFI | Foz do Iguaçu International Airport | |
| Brazil | Rio de Janeiro | GIG | SBGL | Rio de Janeiro–Galeão International Airport | |
| Brazil | São Paulo | GRU | SBGR | São Paulo–Guarulhos International Airport | |
| Chile | Antofagasta | ANF | SCFA | Andrés Sabella Gálvez International Airport | |
| Chile | Hanga Roa | IPC | SCIP | Mataveri International Airport | |
| Chile | Iquique | IQQ | SCDA | Diego Aracena International Airport | Terminated |
| Chile | Santiago | SCL | SCEL | Comodoro Arturo Merino Benítez International Airport | |
| Colombia | Bogotá | BOG | SKBO | El Dorado International Airport | |
| Colombia | Cali | CLO | SKCL | Alfonso Bonilla Aragón International Airport | |
| Colombia | Cartagena | CTG | SKCG | Rafael Núñez International Airport | Terminated |
| Colombia | Medellín | MDE | SKRG | José María Córdova International Airport | |
| Costa Rica | San José | SJO | MROC | Juan Santamaría International Airport | |
| Cuba | Havana | HAV | MUHA | José Martí International Airport | [1] |
| Dominican Republic | Punta Cana | PUJ | MDPC | Punta Cana International Airport | |
| Ecuador | Quito | UIO | SEQM | Mariscal Sucre International Airport | |
| France | Paris | CDG | LFPG | Charles de Gaulle Airport | Terminated |
| Mexico | Cancún | CUN | MMUN | Cancún International Airport | |
| Mexico | Mexico City | MEX | MMMX | Mexico City International Airport | |
| Peru | Arequipa | AQP | SPQU | Rodríguez Ballón International Airport | Focus city |
| Peru | Ayacucho | AYP | SPHO | Coronel FAP Alfredo Mendívil Duarte Airport | |
| Peru | Cajamarca | CJA | SPJR | Mayor General FAP Armando Revoredo Iglesias Airport | |
| Peru | Chiclayo | CIX | SPHI | FAP Captain José Abelardo Quiñones Gonzáles International Airport | |
| Peru | Cusco | CUZ | SPZO | Alejandro Velasco Astete International Airport | Focus city |
| Peru | Iquitos | IQT | SPQT | Coronel FAP Francisco Secada Vignetta International Airport | |
| Peru | Jaen | JAE | SPJE | Jaén Airport | |
| Peru | Jauja | JAU | SPJJ | Francisco Carle Airport | |
| Peru | Juliaca | JUL | SPJL | Inca Manco Cápac International Airport | |
| Peru | Lima | LIM | SPJC | Jorge Chávez International Airport | Hub |
| Peru | Piura | PIU | SPUR | FAP Captain Guillermo Concha Iberico International Airport | |
| Peru | Pucallpa | PCL | SPCL | FAP Captain David Abensur Rengifo International Airport | |
| Peru | Puerto Maldonado | PEM | SPTU | Padre Aldamiz International Airport | |
| Peru | Tacna | TCQ | SPTN | Coronel FAP Carlos Ciriani Santa Rosa International Airport | |
| Peru | Talara | TYL | SPYL | Capitán FAP Víctor Montes Arias International Airport | |
| Peru | Tarapoto | TPP | SPST | Cad. FAP Guillermo del Castillo Paredes Airport | |
| Peru | Trujillo | TRU | SPRU | FAP Captain Carlos Martínez de Pinillos International Airport | |
| Peru | Tumbes | TBP | SPME | Cap. FAP Pedro Canga Rodríguez Airport | |
| Spain | Barcelona | BCN | LEBL | Barcelona–El Prat Airport | |
| Spain | Madrid | MAD | LEMD | Adolfo Suárez Madrid–Barajas Airport | |
| United States | Los Angeles | LAX | KLAX | Los Angeles International Airport | |
| United States | Miami | MIA | KMIA | Miami International Airport | Focus city |
| United States | Orlando | MCO | KMCO | Orlando International Airport | |
| United States | New York City | JFK | KJFK | John F. Kennedy International Airport | |
| United States | San Francisco | SFO | KSFO | San Francisco International Airport | Terminated |
| United States | Washington, D.C. | IAD | KIAD | Washington Dulles International Airport | Terminated |
| Uruguay | Montevideo | MVD | SUMU | Carrasco International Airport | |
| Venezuela | Caracas | CCS | SVMI | Simón Bolívar International Airport | Terminated |
|