KIAA1333

G2E3
Identifiers
AliasesG2E3, KIAA1333, PHF7B, G2/M-phase specific E3 ubiquitin protein ligase
External IDsMGI: 2444298 HomoloGene: 32362 GeneCards: G2E3
Gene location (Human)
Chr.Chromosome 14 (human)[1]
Band14q12Start30,559,123 bp[1]
End30,620,063 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

55632

217558

Ensembl

ENSG00000092140

ENSMUSG00000035293

UniProt

Q7L622

Q5RJY2

RefSeq (mRNA)

NM_001308097
NM_017769

NM_001015099
NM_001167963
NM_001167964

RefSeq (protein)

NP_001295026
NP_060239

NP_001015099
NP_001161435
NP_001161436

Location (UCSC)Chr 14: 30.56 – 30.62 MbChr 12: 51.35 – 51.38 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

G2/M phase-specific E3 ubiquitin-protein ligase is an enzyme that in humans is encoded by the G2E3 gene.[5][6][7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000092140 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035293 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Brooks WS, Helton ES, Banerjee S, Venable M, Johnson L, Schoeb TR, Kesterson RA, Crawford DF (Aug 2008). "G2E3 is a dual function ubiquitin ligase required for early embryonic development". J Biol Chem. 283 (32): 22304–15. doi:10.1074/jbc.M803238200. PMC 2494922. PMID 18511420.
  6. ↑ Brooks WS, Banerjee S, Crawford DF (Feb 2007). "G2E3 is a nucleo-cytoplasmic shuttling protein with DNA damage responsive localization". Exp Cell Res. 313 (4): 665–76. doi:10.1016/j.yexcr.2006.11.020. PMC 1876774. PMID 17239372.
  7. ↑ "Entrez Gene: KIAA1333 KIAA1333".

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
  • Crawford DF, Piwnica-Worms H (2001). "The G(2) DNA damage checkpoint delays expression of genes encoding mitotic regulators". J. Biol. Chem. 276 (40): 37166–77. doi:10.1074/jbc.M103414200. PMID 11483598.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Lehner B, Semple JI, Brown SE, et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. PMID 14667819.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.


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