Iodophenol O-methyltransferase

iodophenol O-methyltransferase
Identifiers
EC number 2.1.1.26
CAS number 37256-95-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, an iodophenol O-methyltransferase (EC 2.1.1.26) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 2-iodophenol S-adenosyl-L-homocysteine + 2-iodophenol methyl ether

Thus, the two substrates of this enzyme are S-adenosyl methionine and 2-iodophenol, whereas its two products are S-adenosylhomocysteine and 2-iodophenol methyl ether.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:2-iodophenol O-methyltransferase.

References

    • Tomita K, Cha CJ, Lardy HA (1964). "Enzymic O-methylation of iodinated phenols and thyroid hormones". J. Biol. Chem. 239: 1202&ndash, 1207. PMID 14165927.
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