Glycoside hydrolase family 53

Glycosyl hydrolase family 53
crystal structure of beta-1,4-galactanase from aspergillus aculeatus at 100k
Identifiers
Symbol Glyco_hydro_53
Pfam PF07745
Pfam clan CL0058
InterPro IPR011683
SCOP 1fob
SUPERFAMILY 1fob
OPM superfamily 117
OPM protein 1hjq
CAZy GH53

In molecular biology, glycoside hydrolase family 53 is a family of glycoside hydrolases.

Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy web site,[4][5] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[6][7]

These enzymes are endo-1,4- beta-galactanases EC 3.2.1.89. The structure of this domain is known [8] and has a TIM barrel fold.

References

  1. ↑ Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon JP, Davies G (July 1995). "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proceedings of the National Academy of Sciences of the United States of America. 92 (15): 7090–4. doi:10.1073/pnas.92.15.7090. PMC 41477. PMID 7624375.
  2. ↑ Davies G, Henrissat B (September 1995). "Structures and mechanisms of glycosyl hydrolases". Structure. 3 (9): 853–9. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779.
  3. ↑ Henrissat B, Bairoch A (June 1996). "Updating the sequence-based classification of glycosyl hydrolases". The Biochemical Journal. 316 ( Pt 2) (Pt 2): 695–6. PMC 1217404. PMID 8687420.
  4. ↑ "Home". CAZy.org. Retrieved 2018-03-06.
  5. ↑ Lombard V, Golaconda Ramulu H, Drula E, Coutinho PM, Henrissat B (January 2014). "The carbohydrate-active enzymes database (CAZy) in 2013". Nucleic Acids Research. 42 (Database issue): D490–5. doi:10.1093/nar/gkt1178. PMID 24270786.
  6. ↑ "Glycoside Hydrolase Family 53". CAZypedia.org. Retrieved 2018-03-06.
  7. ↑ "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes". Glycobiology. 28 (1): 3–8. December 2018. doi:10.1093/glycob/cwx089. PMID 29040563.
  8. ↑ Ryttersgaard C, Lo Leggio L, Coutinho PM, Henrissat B, Larsen S (December 2002). "Aspergillus aculeatus beta-1,4-galactanase: substrate recognition and relations to other glycoside hydrolases in clan GH-A". Biochemistry. 41 (51): 15135–43. doi:10.1021/bi026238c. PMID 12484750.
This article incorporates text from the public domain Pfam and InterPro: IPR011683
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.