Glucosyl-3-phosphoglycerate synthase

Glucosyl-3-phosphoglycerate synthase
Identifiers
EC number 2.4.1.266
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Glucosyl-3-phosphoglycerate synthase (EC 2.4.1.266, GpgS protein, GPG synthase, glucosylphosphoglycerate synthase) is an enzyme with systematic name NDP-glucose:3-phospho-D-glycerate 2-alpha-D-glucosyltransferase.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction

NDP-glucose + 3-phospho-D-glycerate NDP + 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate

The enzyme is involved in biosynthesis of 2-O-(alpha-D-glucopyranosyl)-D-glycerate.

References

  1. ↑ Costa, J.; Empadinhas, N.; da Costa, M.S. (2007). "Glucosylglycerate biosynthesis in the deepest lineage of the bacteria: characterization of the thermophilic proteins GpgS and GpgP from Persephonella marina". J. Bacteriol. 189 (5): 1648–1654. doi:10.1128/JB.00841-06. PMC 1855766. PMID 17189358.
  2. ↑ Costa, J.; Empadinhas, N.; Goncalves, L.; Lamosa, P.; Santos, H.; da Costa, M.S. (2006). "Characterization of the biosynthetic pathway of glucosylglycerate in the archaeon Methanococcoides burtonii". J. Bacteriol. 188 (3): 1022–1030. doi:10.1128/JB.188.3.1022-1030.2006. PMC 1347341. PMID 16428406.
  3. ↑ Empadinhas, N.; Albuquerque, L.; Mendes, V.; Macedo-Ribeiro, S.; da Costa, M.S. (2008). "Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase". FEMS Microbiol. Lett. 280 (2): 195–202. doi:10.1111/j.1574-6968.2007.01064.x. PMID 18221489.
  4. ↑ Pereira, P.J.; Empadinhas, N.; Albuquerque, L.; Sa-Moura, B.; da Costa, M.S.; Macedo-Ribeiro, S. (2008). Song, Haiwei, ed. "Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis". PLoS ONE. 3 (11): #e3748–e3748. Bibcode:2008PLoSO...3.3748P. doi:10.1371/journal.pone.0003748. PMC 2581804. PMID 19015727.
  5. ↑ Gest, P.; Kaur, D.; Pham, H.T.; van der Woerd, M.; Hansen, E.; Brennan, P.J.; Jackson, M.; Guerin, M.E. (2008). "Preliminary crystallographic analysis of GpgS, a key glucosyltransferase involved in methylglucose lipopolysaccharide biosynthesis in Mycobacterium tuberculosis". Acta Crystallographica Section F. 64 (Pt 12): 1121–1124. doi:10.1107/S1744309108032892. PMC 2593697. PMID 19052364.
  6. ↑ Kaur, D.; Pham, H.; Larrouy-Maumus, G.; Riviere, M.; Vissa, V.; Guerin, M.E.; Puzo, G.; Brennan, P.J.; Jackson, M. (2009). Herman, Christophe, ed. "Initiation of methylglucose lipopolysaccharide biosynthesis in mycobacteria". PLoS ONE. 4 (5): #e544–e5447. Bibcode:2009PLoSO...4.5447K. doi:10.1371/journal.pone.0005447. PMC 2674218. PMID 19421329.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.