GLRA2

GLRA2
Identifiers
AliasesGLRA2, GLR, glycine receptor alpha 2
External IDsMGI: 95748 HomoloGene: 31070 GeneCards: GLRA2
Gene location (Human)
Chr.X chromosome (human)[1]
BandXp22.2Start14,529,298 bp[1]
End14,731,812 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

2742

237213

Ensembl

ENSG00000101958

ENSMUSG00000018589

UniProt

P23416

Q7TNC8

RefSeq (mRNA)

NM_001118885
NM_001118886
NM_001171942
NM_002063

NM_183427
NM_001357099
NM_001357100

RefSeq (protein)

NP_001112357
NP_001112358
NP_001165413
NP_002054

NP_906272
NP_001344028
NP_001344029

Location (UCSC)Chr X: 14.53 – 14.73 MbChr X: 165.13 – 165.33 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Glycine receptor subunit alpha-2 is a protein that in humans is encoded by the GLRA2 gene.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000101958 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000018589 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: GLRA2 glycine receptor, alpha 2".

Further reading

  • Grenningloh G, Schmieden V, Schofield PR, et al. (1990). "Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes". EMBO J. 9 (3): 771–6. PMC 551735. PMID 2155780.
  • Monani U, Burghes AH (1997). "Structure of the human alpha 2 subunit gene of the glycine receptor--use of vectorette and Alu-exon PCR". Genome Res. 6 (12): 1200–6. doi:10.1101/gr.6.12.1200. PMID 8973915.
  • Cummings CJ, Dahle EJ, Zoghbi HY (1998). "Analysis of the genomic structure of the human glycine receptor alpha2 subunit gene and exclusion of this gene as a candidate for Rett syndrome". Am. J. Med. Genet. 78 (2): 176–8. doi:10.1002/(SICI)1096-8628(19980630)78:2<176::AID-AJMG16>3.0.CO;2-K. PMID 9674912.
  • Feng J, Craddock N, Jones IR, et al. (2001). "Systematic screening for mutations in the glycine receptor alpha2 subunit gene (GLRA2) in patients with schizophrenia and other psychiatric diseases". Psychiatr. Genet. 11 (1): 45–8. doi:10.1097/00041444-200103000-00009. PMID 11409700.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Davies DL, Crawford DK, Trudell JR, et al. (2004). "Multiple sites of ethanol action in alpha1 and alpha2 glycine receptors suggested by sensitivity to pressure antagonism". J. Neurochem. 89 (5): 1175–85. doi:10.1111/j.1471-4159.2004.02390.x. PMID 15147510.
  • Miller PS, Harvey RJ, Smart TG (2005). "Differential agonist sensitivity of glycine receptor alpha2 subunit splice variants". Br. J. Pharmacol. 143 (1): 19–26. doi:10.1038/sj.bjp.0705875. PMC 1575261. PMID 15302677.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Miller PS, Da Silva HM, Smart TG (2006). "Molecular basis for zinc potentiation at strychnine-sensitive glycine receptors". J. Biol. Chem. 280 (45): 37877–84. doi:10.1074/jbc.M508303200. PMID 16144831.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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