Fosfluconazole
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AHFS/Drugs.com | International Drug Names |
Routes of administration | IV |
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Formula | C13H13F2N6O4P |
Molar mass | 386.25 g/mol |
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Fosfluconazole (INN) is a water-soluble phosphate prodrug of fluconazole — a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
The phosphate ester bond is hydrolyzed by the action of a phosphatase — an enzyme that removes a phosphate group from its substrate by hydrolyzing phosphoric acid monoesters into a phosphate ion and a molecule with a free hydroxyl group (dephosphorylation).
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