Fluoroiodomethane

Fluoroiodomethane

Names
Preferred IUPAC name Fluoro(iodo)methane
Other names Fluoroiodomethane Fluoro-iodo-methane Fluoromethyl iodide
Identifiers
CAS Number	373-53-5 Y
3D model (JSmol)	Interactive image
ChemSpider	10329326 Y
ECHA InfoCard	100.201.539
InChI InChI=1S/CH2FI/c2-1-3/h1H2 Y Key: XGVXNTVBGYLJIR-UHFFFAOYSA-N Y InChI=1/CH2FI/c2-1-3/h1H2
SMILES FCI
Properties
Chemical formula	CH2FI
Molar mass	159.93 g/mol
Boiling point	53.4 °C (128.1 °F; 326.5 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Fluoroiodomethane is a mixed halomethane, more exactly fluoroiodocarbon (FIC).

Synthesis

Fluoroiodomethane can be prepared from iodoacetic acid.^[1]

Applications

Its isotopomer [¹⁸F]fluoroiodomethane (PubChem 451313) is a synthetic precursor for fluoromethylation of radiopharmaceuticals.

Also proposal of its use as a safe high-performance foam blowing agent exists.^[2]

Notes

References

• Zheng L.; Berridge M. S. (January 2000). "Synthesis of [¹⁸F]fluoromethyl iodide, a synthetic precursor for fluoromethylation of radiopharmaceuticals". Applied Radiation and Isotopes. 52 (1): 55–61(7). doi:10.1016/S0969-8043(99)00061-5. PMID 10670923. Retrieved 2007-06-29.
• Chin F. T.; Morse Ch. L.; Shetty H. U.; Pike V. W. (December 2005). "Automated radiosynthesis of [18F]SPA-RQ for imaging human brain NK1 receptors with PET". Journal of Labelled Compounds and Radiopharmaceuticals. 49 (1): 17–31(15). doi:10.1002/jlcr.1016. Retrieved 2007-06-29.
• Tedder, J. M.; Sloan, J. P.; Walton, J. C. (1975). "Free Radical Addition to Olefins, Part XVII. Addition of Fluoroiodomethane to Fluoroethylenes". Journal of the Chemical Society: 1846–1850.