Envelysin

Envelysin
Identifiers
EC number 3.4.24.12
CAS number 50812-13-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Envelysin (EC 3.4.24.12, sea-urchin-hatching proteinase, hatching enzyme, chorionase, chorion-digesting proteinase, chymostrypsin, sea urchin embryo hatching enzyme) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins of the fertilization envelope and dimethylcasein

This enzyme is a glycoprotein from various members of the class Echinoidea.

References

  1. Barrett D, Edwards BF (1976). "Hatching enzyme of the sea urchin Strongylocentrotus purpuratus". Methods in Enzymology. 45: 354–73. doi:10.1016/s0076-6879(76)45032-2. PMID 1012003.
  2. Lepage T, Gache C (March 1989). "Purification and characterization of the sea urchin embryo hatching enzyme". The Journal of Biological Chemistry. 264 (9): 4787–93. PMID 2925668.
  3. Lepage T, Gache C (September 1990). "Early expression of a collagenase-like hatching enzyme gene in the sea urchin embryo". The EMBO Journal. 9 (9): 3003–12. PMC 552018. PMID 2167841.
  4. Nomura K, Tanaka H, Kikkawa Y, Yamaguchi M, Suzuki N (June 1991). "The specificity of sea urchin hatching enzyme (envelysin) places it in the mammalian matrix metalloproteinase family". Biochemistry. 30 (25): 6115–23. doi:10.1021/bi00239a005. PMID 1711895.
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