Didecyldimethylammonium chloride

Didecyldimethylammonium chloride
Names
IUPAC name
didecyl-dimethylammonium chloride
Other names
  • DDAC
  • Dimethyldidecylammonium chloride[1]
  • 1-Decanaminium[1]
  • N-decyl-N,N-dimethyl-, chloride[1]
  • Didecyldimethylammonium chloride[1]
  • Didecyl dimethyl ammonium chloride[1]
  • Quaternium-12[1]

Ammonium, didecyldimethyl-, chloride[1]

Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.027.751
UNII
Properties
C22H48ClN
Molar mass 362.08 g/mol
Appearance liquid[2]
Density 0.87 g/cm3 (20 °C)[2]
Pharmacology
D08AJ06 (WHO)
Hazards
Main hazards corrosive [2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Didecyldimethylammonium chloride (DDAC) is an antiseptic/disinfectant that is used in many biocidal applications. They cause disruption of intermolecular interactions and dissociation of lipid bilayers. They are broad spectrum bactericidal and fungicidal and can be used as disinfectant cleaner for linen, recommended for use in hospitals, hotels and industries. It is also used in gynaecology, surgery, ophthalmology, pediatrics, OT, and for the sterilization of surgical instruments, endoscopes and surface disinfection.

In mice this disinfectant was found to cause infertility and birth defects [3], but the study conclusions are contradicted by an existing toxicology data set on quaternary ammonia compounds which has been extensively and independently reviewed by multiple regulatory authorities, including the U.S. Environmental Protection Agency (U.S. EPA) and the EU Commission [4]

See also

References

  1. 1 2 3 4 5 6 7 "Didecyl dimethyl ammonium chloride", Household Products Database, US Department of Health and Human Services, 2016
  2. 1 2 3 Record of didecyldimethylammonium chloride in the GESTIS Substance Database of the Institute for Occupational Safety and Health, accessed on 2 November 2007.
  3. ↑ Brendan Maher (2008). "Lab disinfectant harms mouse fertility". Nature. 453 (7198): 964. doi:10.1038/453964a. PMID 18563110.
  4. ↑ Office of Prevention, Pesticides and Toxic Substances, US EPA (August 2006). "Reregistration Eligibility Decision for Aliphatic Alkyl Quaternaries (DDAC)". EPA739-R-06-008.


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