DNA-deoxyinosine glycosylase

DNA-deoxyinosine glycosylase
Identifiers
EC number 3.2.2.15
CAS number 68247-62-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

DNA-deoxyinosine glycosylase (EC 3.2.2.15, DNA(hypoxanthine) glycohydrolase, deoxyribonucleic acid glycosylase, hypoxanthine-DNA glycosylase) is an enzyme with systematic name DNA-deoxyinosine deoxyribohydrolase.[1] This enzyme catalyses the following chemical reaction

Hydrolyses DNA and polynucleotides, releasing free hypoxanthine

References

  1. Karran, P.; Lindahl, T. (1978). "Enzymatic excision of free hypoxanthine from polydeoxynucleotides and DNA containing deoxyinosine monophosphate residues". J. Biol. Chem. 253 (17): 5877–5879. PMID 98523.


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