D-iditol 2-dehydrogenase
| D-iditol 2-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.15 | ||||||||
| CAS number | 9028-22-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a D-iditol 2-dehydrogenase (EC 1.1.1.15) is an enzyme that catalyzes the chemical reaction
- D-iditol + NAD+ D-sorbose + NADH + H+
Thus, the two substrates of this enzyme are D-iditol and NAD+, whereas its 3 products are D-sorbose, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-iditol:NAD+ 2-oxidoreductase. This enzyme is also called D-sorbitol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism.
References
- Shaw DRD (1956). "Polyol dehydrogenases. 3. Galactitol dehydrogenase and D-iditol dehydrogenase". Biochem. J. 64 (3): 394&ndash, 405. PMC 1199749. PMID 13373783.
This article is issued from
Wikipedia.
The text is licensed under Creative Commons - Attribution - Sharealike.
Additional terms may apply for the media files.