Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase

Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase
Identifiers
EC number 2.4.1.254
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase (EC 2.4.1.254, BpUGT94B1, UDP-glucuronic acid:anthocyanin glucuronosyltransferase, UDP-glucuronic acid:anthocyanidin 3-glucoside 2'-O-beta-glucuronosyltransferase, BpUGAT, UDP-D-glucuronate:cyanidin-3-O-beta-glucoside 2-O-beta-glucuronosyltransferase) is an enzyme with systematic name UDP-D-glucuronate:cyanidin-3-O-beta-D-glucoside 2-O-beta-D-glucuronosyltransferase.[1][2] This enzyme catalyses the following chemical reaction

UDP-D-glucuronate + cyanidin 3-O-beta-D-glucoside UDP + cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside

The enzyme is highly specific for cyanidin 3-O-glucosides and UDP-D-glucuronate.

References

  1. ↑ Sawada, S.; Suzuki, H.; Ichimaida, F.; Yamaguchi, M.A.; Iwashita, T.; Fukui, Y.; Hemmi, H.; Nishino, T.; Nakayama, T. (2005). "UDP-glucuronic acid:anthocyanin glucuronosyltransferase from red daisy (Bellis perennis) flowers. Enzymology and phylogenetics of a novel glucuronosyltransferase involved in flower pigment biosynthesis". J. Biol. Chem. 280: 899–906. doi:10.1074/jbc.m410537200. PMID 15509561.
  2. ↑ Osmani, S.A.; Bak, S.; Imberty, A.; Olsen, C.E.; Møller, B.L. (2008). "Catalytic key amino acids and UDP-sugar donor specificity of a plant glucuronosyltransferase, UGT94B1: molecular modeling substantiated by site-specific mutagenesis and biochemical analyses". Plant Physiol. 148: 1295–1308. doi:10.1104/pp.108.128256. PMC 2577238. PMID 18829982.
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