Cellulose 1,4-beta-cellobiosidase

Cellulose 1,4-beta-cellobiosidase (non-reducing end)
Cellobiohydrolase monomer, Trichoderma reesei
Identifiers
EC number 3.2.1.91
CAS number 37329-65-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Cellulose 1,4-beta-cellobiosidase (non-reducing end) (EC 3.2.1.91, exo-cellobiohydrolase, beta-1,4-glucan cellobiohydrolase, beta-1,4-glucan cellobiosylhydrolase, 1,4-beta-glucan cellobiosidase, exoglucanase, avicelase, CBH 1, C1 cellulase, cellobiohydrolase I, cellobiohydrolase, exo-beta-1,4-glucan cellobiohydrolase, 1,4-beta-D-glucan cellobiohydrolase, cellobiosidase) is an enzyme with systematic name 4-beta-D-glucan cellobiohydrolase (non-reducing end).[1][2][3][4] This enzyme catalyses the following chemical reaction

Hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing [cellobiose] from the non-reducing ends of the chains

References

  1. Berghem LE, Pettersson LG (August 1973). "The mechanism of enzymatic cellulose degradation. Purification of a cellulolytic enzyme from Trichoderma viride active on highly ordered cellulose". European Journal of Biochemistry. 37 (1): 21–30. doi:10.1111/j.1432-1033.1973.tb02952.x. PMID 4738092.
  2. Eriksson KE, Pettersson B (February 1975). "Extracellular enzyme system utilized by the fungus Sporotrichum pulverulentum (Chrysosporium lignorum) for the breakdown of cellulose. 3. Purification and physico-chemical characterization of an exo-1,4-beta-glucanase". European Journal of Biochemistry. 51 (1): 213–8. doi:10.1111/j.1432-1033.1975.tb03921.x. PMID 235428.
  3. Halliwell G, Griffin M, Vincent R (April 1972). "The role of component C 1 in cellulolytic systems". The Biochemical Journal. 127 (2): 43P. PMC 1178673. PMID 5076675.
  4. Zverlov VV, Velikodvorskaya GV, Schwarz WH, Bronnenmeier K, Kellermann J, Staudenbauer WL (June 1998). "Multidomain structure and cellulosomal localization of the Clostridium thermocellum cellobiohydrolase CbhA". Journal of Bacteriology. 180 (12): 3091–9. PMID 9620957.
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