Cardiotoxin III

Cardiotoxin III

Cardiotoxin III (CTX III, also known as cytotoxin 3) is a sixteen amino-acid polypeptide toxin from the Taiwan Cobra Naja naja atra.

Recent evidence has shown that CTX III may induce apoptosis in K562 cells via the release of cytochrome c.[1]

This protein belongs to large family of snake venom toxins.[2]

References

  1. ↑ Yang SH, Chien CM, Lu MC, Lu YJ, Wu ZZ, Lin SR (July 2005). "Cardiotoxin III induces apoptosis in K562 cells through a mitochondrial-mediated pathway". Clin. Exp. Pharmacol. Physiol. 32 (7): 515–20. doi:10.1111/j.1440-1681.2005.04223.x. PMID 16026508.
  2. ↑ "Superfamily » 2.2.39. Snake toxin-like (2 families) - Orientations of Proteins in Membranes (OPM) database". Retrieved 2008-12-13.


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