Biliverdin reductase A

biliverdin reductase A
Biliverdin reductase A dimer, Human
Identifiers
EC number 1.3.1.24
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
BLVRA
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesBLVRA, BLVR, BVR, BVRA, biliverdin reductase A
External IDsMGI: 88170 HomoloGene: 572 GeneCards: BLVRA
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7p13Start43,758,680 bp[1]
End43,807,342 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

644

109778

Ensembl

ENSG00000106605

ENSMUSG00000001999

UniProt

P53004

Q9CY64

RefSeq (mRNA)

NM_000712
NM_001253823

NM_026678

RefSeq (protein)

NP_000703
NP_001240752

NP_080954

Location (UCSC)Chr 7: 43.76 – 43.81 MbChr 2: 127.07 – 127.1 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Biliverdin reductase A is a protein that in humans is encoded by the BLVRA gene.[5]

Function

The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH.[5]

Clinical significance

Mutations in this gene are associated with hyperbiliverdinemia.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000106605 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001999 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 3 "Entrez Gene: Biliverdin reductase A".

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.