Beta-amyrin 24-hydroxylase

Beta-amyrin 24-hydroxylase
Identifiers
EC number 1.14.99.43
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Beta-amyrin 24-hydroxylase (EC 1.14.99.43, sophoradiol 24-hydroxylase, CYP93E1) is an enzyme with systematic name beta-amyrin,AH2:oxygen oxidoreductase (24-hydroxylating).[1] This enzyme catalyses the following chemical reaction

(1) beta-amyrin + AH2 + O2 24-hydroxy-beta-amyrin + A + H2O
(2) sophoradiol + AH2 + O2 24-hydroxysophoradiol + A + H2O

Beta-amyrin 24-hydroxylase is heme-thiolate protein (P-450).

References

  1. Shibuya, M.; Hoshino, M.; Katsube, Y.; Hayashi, H.; Kushiro, T.; Ebizuka, Y. (2006). "Identification of β-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay". FEBS J. 273 (5): 948–959. doi:10.1111/j.1742-4658.2006.05120.x. PMID 16478469.
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