Alpha-humulene 10-hydroxylase

Alpha-humulene 10-hydroxylase
Identifiers
EC number 1.14.13.150
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Alpha-humulene 10-hydroxylase (EC 1.14.13.150, CYP71BA1) is an enzyme with systematic name alpha-humulene,NADPH:oxygen 10-oxidoreductase.[1] This enzyme catalyses the following chemical reaction

alpha-humulene + O2 + NADPH + H+ 10-hydroxy-alpha-humulene + NADP+ + H2O

Alpha-humulene 10-hydroxylase requires cytochrome P-450.

References

  1. Yu, F.; Okamoto, S.; Harada, H.; Yamasaki, K.; Misawa, N.; Utsumi, R. (2011). "Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis". Cell. Mol. Life Sci. 68 (6): 1033–1040. doi:10.1007/s00018-010-0506-4. PMID 20730551.
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