Alcohol-forming fatty acyl-CoA reductase

Alcohol-forming fatty acyl-CoA reductase
Identifiers
EC number 1.2.1.84
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Alcohol-forming fatty acyl-CoA reductase (EC 1.2.1.84, FAR (gene)) is an enzyme with systematic name long-chain acyl-CoA:NADPH reductase.[1] This enzyme catalyses the following chemical reaction

a long-chain acyl-CoA + 2 NADPH + 2 H+ a long-chain alcohol + 2 NADP+ + coenzyme A

The enzyme has been characterized from the plant Simmondsia chinensis.

References

  1. Metz, J.G.; Pollard, M.R.; Anderson, L.; Hayes, T.R.; Lassner, M.W. (2000). "Purification of a jojoba embryo fatty acyl-coenzyme A reductase and expression of its cDNA in high erucic acid rapeseed". Plant Physiol. 122 (3): 635–644. doi:10.1104/pp.122.3.635. PMC 58898. PMID 10712526.
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