8-oxoguanine deaminase

8-oxoguanine deaminase
Identifiers
EC number 3.5.4.32
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

8-oxoguanine deaminase (EC 3.5.4.32, 8-OGD) is an enzyme with systematic name 8-oxoguanine aminohydrolase.[1] This enzyme catalyses the following chemical reaction

8-oxoguanine + H2O urate + NH3

Zn2+ is bound in the active site.

References

  1. Hall, R.S.; Fedorov, A.A.; Marti-Arbona, R.; Fedorov, E.V.; Kolb, P.; Sauder, J.M.; Burley, S.K.; Shoichet, B.K.; Almo, S.C.; Raushel, F.M. (2010). "The hunt for 8-oxoguanine deaminase". J. Am. Chem. Soc. 132: 1762–1763. doi:10.1021/ja909817d. PMC 2820149. PMID 20088583.
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