Trans-acenaphthene-1,2-diol dehydrogenase

In enzymology, a trans-acenaphthene-1,2-diol dehydrogenase (EC 1.10.1.1) is an enzyme that catalyzes the chemical reaction

(+/-)-trans-acenaphthene-1,2-diol + 2 NADP+ acenaphthenequinone + 2 NADPH + 2 H+
trans-acenaphthene-1,2-diol dehydrogenase
Identifiers
EC number1.10.1.1
CAS number51901-21-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are (+/-)-trans-acenaphthene-1,2-diol and NADP+, whereas its 3 products are acenaphthenequinone, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on diphenols and related substances as donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+/-)-trans-acenaphthene-1,2-diol:NADP+ oxidoreductase. This enzyme is also called trans-1,2-acenaphthenediol dehydrogenase.

References

    • Hopkins RP, Drummond EC, Callaghan P (1973). "Dehydrogenation of trans-acenaphthene-1,2-diol by liver cytosol preparations". Biochem. Soc. Trans. 1: 989–991.


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